NB100-64226 MHC Class II RT1B (positive on a, I, n haplotype) antibody

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Mouse anti Rat MHC Class II RT1B F17-23-2


Product Description for MHC Class II RT1B

Mouse anti Rat MHC Class II RT1B F17-23-2.
Properties: (positive on a, I, n haplotype)
Presentation: FITC
Product is tested for Flow Cytometry.

Properties for MHC Class II RT1B

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation FITC
Reactivity Rt
Applications F
Clonality Monoclonal
Clone F17-23-2
Host Mouse
Isotype IgG1
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Partially purified rat MHC antigens
Property positive on a, I, n haplotype
Isotype control SM20F (for use in rat samples)
Application flow cytometry / FACS analysis, Flow cytometry / FACS analysis, flow cytometry / FACS analysis 1:5
Background MHC Class II antigens are heterodimers consisting of one alpha chain(31-34kD) and one beta chain (26-29kD). The family of monoclonal antibodies (ER-TR 3, ER-TR 2, ER-TR 1) detect MHC class II antigens encoded by the murine Ia region of the H-2 complex, corresponding to the human HLA-DR region. MHC Class II antigens are a valuable tool for studying T helper cell interaction with class II positive antigen presenting cells (dendritic cells, B cells, macrophages) and offer new possibilities for studying the development of T helper cells since these antibodies also stain stromal cells in the thymus. MHC Class II antigens are also inducible on a number of other cells (endothelium and epithelial cells) by interferon gamma.
Concentration 0.1 mg/ml
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
protein G purified
Buffer System:
0.09% Sodium Azide
protein G purified
Recognizes the rat RT1B MHC class II antigen, reacting with haplotypes a, l and n expressed on rat strains including DA, LEW, and BN. This product is routinely tested in flow cytometry on DA rat splenocytes.
Gene ID 294274

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