NB100-64238 MHC Class II RT1B antibody

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0.1 mg / €370.00

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Mouse anti Rat MHC Class II RT1B OX-6

Product Description for MHC Class II RT1B

Mouse anti Rat MHC Class II RT1B OX-6.
Presentation: FITC
Product is tested for Flow Cytometry.

Properties for MHC Class II RT1B

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation FITC
Reactivity Rt
Applications F
Clonality Monoclonal
Clone OX-6
Host Mouse
Isotype IgG1
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Rat thymocyte membrane glycoproteins
Application flow cytometry / FACS analysis, Flow cytometry / FACS analysis, flow cytometry / FACS analysis 1:10
Background MHC Class II antigens are heterodimers consisting of one alpha chain(31-34kD) and one beta chain (26-29kD). The family of monoclonal antibodies (ER-TR 3, ER-TR 2, ER-TR 1) detect MHC class II antigens encoded by the murine Ia region of the H-2 complex, corresponding to the human HLA-DR region. MHC Class II antigens are a valuable tool for studying T helper cell interaction with class II positive antigen presenting cells (dendritic cells, B cells, macrophages) and offer new possibilities for studying the development of T helper cells since these antibodies also stain stromal cells in the thymus. MHC Class II antigens are also inducible on a number of other cells (endothelium and epithelial cells) by interferon gamma.
Concentration 0.1 mg/ml
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
protein G purified
Buffer System:
0.09% Sodium Azide
protein G purified
NB100-64238 recognizes a monomorphic determinant of the rat I-A antigen present on B lymphocytes, dendritic cells, some macrophages and certain epithelial cells. This antibody cross reacts with certain mouse strains of MHC haplotypes k and s. Analysis of recombinant mouse strains showed that the determinants mapped to the I-A region (1). The clone does not react with the Rat BDIX strain. This product is routinely tested in flow cytometry on rat splenocytes.

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