NBP1-50112 MIF antibody

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0.1 mg / €420.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Mouse anti Human MIF LN-5

NBP1-50112

Product Description for MIF

Mouse anti Human MIF LN-5.
Presentation: Purified
Product is tested for Frozen Sections, Paraffin Sections.

Properties for MIF

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms GLIF, Glycosylation-inhibiting factor, MMIF, Macrophage migration inhibitory factor, Phenylpyruvate tautomerase
Presentation Purified
Reactivity Hu
Applications C, P
Clonality Monoclonal
Clone LN-5
Host Mouse
Isotype IgM
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Immunogen:
The antibody reacts with Human Macrophages.
Background TNF-alpha is secreted by macrophages, monocytes, neutrophils, T-cells (principally CD4+), and NK-cells. Many transformed cell lines also secrete TNF-alpha. Monomeric human TNF-alpha is a 157 amino acid protein (non-glycosylated) with a reported molecular weight of 17 kD. TNF-alpha forms multimeric complexes; stable trimers are most common in solution. A 26 kD membrane form of TNF-alpha has also been described. TNF-alpha binding to surface receptors elicits a wide array of biologic activities including: cytolysis and cytostasis of many tumor cell lines in vitro, hemorraghic necrosis of tumors in vivo, increased fibroblast proliferation, and enhanced chemotaxis and phagocytosis in neutrophils. The MAb11 antibody can neutralize the bioactivity of natural or recombinant TNF-alpha.
Storage Store at 4C short term. Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Format
Purification:
IgM purified
Buffer System:
100 ug purified material in PBS with 0.05% sodium azide Concentration: 100 ug/ml.
State:
Purified
Gene ID 4282

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