AM31831PU-N Mitochondria antibody

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0.1 ml / €340.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Mouse anti Human Mitochondria 113-1

Product Description for Mitochondria

Mouse anti Human Mitochondria 113-1.
Presentation: Ig Fraction
Product is tested for Paraffin Sections, Frozen Sections, Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot.

Properties for Mitochondria

Product Category Primary Antibodies
Quantity 0.1 ml
Synonyms Mitochondrial Marker
Presentation Ig Fraction
Reactivity Hu
Applications C, ICC/IF, P, WB
Clonality Monoclonal
Clone 113-1
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Immunogen:
Human cell homogenate
Application Western Blot: 1/1,000.
Immunofluorescence: 1/800.
Immunohistochemistry: 1/800.
The antibody works on Acetone fixed and 2% paraformaldehyde fixed cells.
The antibody also works for Immunohistochemistry on 2% paraformaldehyde fixed (5-10 minutes) Cryostat sections.
Successful use in Immunohistochemistry on Formalin-Fixed, Paraffin-Embedded was reported by some researchers.
Background Mitochondria are most commonly known as the power plants of the cell as they produce ATP, but they are also involved in many other important cellular processes such as cell signaling, growth and differentiation (McBride et al., 2006). In addition, mitochondria have been shown to play a role in apoptosis (Green 1998).
General Readings
  1. McBride HM, Neuspiel M, Wasiak S (2006) Mitochondria: More than just a powerhouse. Curr Biol. 16(14):R551-60.
  2. Green DR (1998) Apoptotic pathways: the roads to ruin. Cell 94(6):695-8.
Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Format
Purification:
Immunoglobulin Fractionation
State:
Liquid Total IgG fraction
Ig Fraction
Species Reactivity
Species reactivity (tested):
Human.
Specificity
Specificity:
Specific for Human Mitochondria in all cell types.
This antibody is an excellent marker for Human cells in xenographic model research.
It reacts specifically with Human cells, including neurons and embryonic stem cells.
It does not react with Mouse or Rat mitochondria.

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