discontinued

NBP1-58155 MLH3 antibody

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50 µg / €390.00

Quick Overview

Rabbit anti Human MLH3

Product Description for MLH3

Rabbit anti Human MLH3.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for MLH3

Product Category Primary Antibodies
Quantity 50 µg
Presentation Aff - Purified
Reactivity Hu
Applications WB
Clonality Polyclonal
Host Rabbit
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
Q2M1Z1
Immunogen:
Synthetic peptides corresponding to MLH3(mutL homolog 3 (E. coli)) The peptide sequence was selected from the middle region of MLH3. Peptide sequence SMQVLQQVDNKFIACLMSTKTEENGEADSYEKQQAQGSGRKKLLSSTLIP.
GeneID:
27030
Background This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. MLH3 functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The protein encoded by this gene functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.
Storage Store at -20C. Avoid freeze-thaw cycles.
Format
Purification:
Peptide affinity purified
Buffer System:
This product is lyophilized and contains PBS and 2% Sucrose. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml.
State:
Aff - Purified
Gene ID 27030

Accessory Products

Proteins and/or Positive Controls

Positive controls for MLH3 (1 products)

Catalog No. Species Pres. Purity   Source  

MLH3 overexpression lysate

MLH3 overexpression lysate
0.1 mg / €480.00
  OriGene Technologies, Inc.
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