NB120-3094 MOSP antibody

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Mouse anti Feline, Human, Monkey, Mouse, Rat MOSP CE1


Product Description for MOSP

Mouse anti Feline, Human, Monkey, Mouse, Rat MOSP CE1.
Product is tested for Frozen Sections, Immunocytochemistry/Immunofluorescence.

Properties for MOSP

Product Category Primary Antibodies
Quantity 0.5 ml
Reactivity Fe, Hu, Mky, Ms, Rt
Applications C, ICC/IF
Clonality Monoclonal
Clone CE1
Host Mouse
Isotype IgM
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Glial membrane proteins followed by rat CNS white matter.
Application IF, IHC-Fr
Background Myelin / Oligodendrocyte Specific Protein (MOSP) (pI of ~6.7) is found exclusively on oligodendrocytes and myelin in the central nervous system (CNS). Myelin is produced by oligodendrocytes in the CNS and Schwann cells in the peripheral nervous system (PNS). Defining the differences between CNS and PNS myelin may provide insights into the process of myelination and the pathogenesis of certain idiopathic diseases involving myelin such as multiple sclerosis, certain leukodystrophies, and other myelinopathies. On demyelination, immunoreactivity for MOSP, like MBP, is lost.
Concentration 0.2 mg/ml
General Readings General / background references:Dyer CA et al. Myelin/oligodendrocyte-specific protein: a novel surface membrane protein that associates with microtubules. J Neurosci Res 28:607-13 (1991). PubMed PMID: 1870160
Buffer System:
10mM PBS, pH7.4, 0.2%BSA, 0.09% sodium azide
Cross-reacts with Human, Rat, Mouse, Cat, Chicken, Monkey and Ferret.Not yet tested in other species.

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