NB120-3369 MRP1 antibody

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Mouse anti MRP1 QCRL1


Product Description for MRP1

Mouse anti MRP1 QCRL1.
Presentation: Purified
Product is tested for Frozen Sections, Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot, Flow Cytometry, Paraffin Sections.

Properties for MRP1

Product Category Primary Antibodies
Quantity 0.25 ml
Presentation Purified
Applications C, F, ICC/IF, P, WB
Clonality Monoclonal
Clone QCRL1
Host Mouse
Isotype IgG1
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Membranes prepared from the human small cell lung cancer cell line H68AR.
Isotype control AM03095PU-N
Application FACS, ICC, IHC-Fr, IHC-P, WB
General Readings General / background references:Hipfner DR et al. Monoclonal antibodies that inhibit the transport function of the 190-kDa multidrug resistance protein, MRP. Localization of their epitopes to the nucleotide-binding domains of the protein. J Biol Chem 274:15420-6 (1999). PubMed PMID: 10336431
Filipits M et al. Expression of the multidrug resistance protein (MRP1) in breast cancer. Anticancer Res 19:5043-9 (1999). PubMed PMID: 10697508
Wright SR et al. Immunohistochemical detection of multidrug resistance protein in human lung cancer and normal lung. Clin Cancer Res 4:2279-89 (1998). PubMed PMID: 9748150
Hipfner DR et al. Epitope mapping of monoclonal antibodies specific for the 190-kDa multidrug resistance protein (MRP). Br J Cancer 78:1134-40 (1998). PubMed PMID: 9820168
Filipits M et al. Immunocytochemical detection of the multidrug resistance-associated protein and P-glycoprotein in acute myeloid leukemia: impact of antibodies, sample source and disease status. Leukemia 11:1073-7 (1997). PubMed PMID: 9204994
Fillpits M et al. Expression of the multidrug resistance-associated protein (MRP) gene in colorectal carcinomas. Br J Cancer 75:208-12 (1997). PubMed PMID: 9010028
Hipfner DR et al. Location of a protease-hypersensitive region in the multidrug resistance protein (MRP) by mapping of the epitope of MRP-specific monoclonal antibody QCRL-1. Cancer Res 56:3307-14 (1996). PubMed PMID: 8764126
Filipits M et al. MRP and MDR1 gene expression in primary breast carcinomas. Clin Cancer Res 2:1231-7 (1996). PubMed PMID: 9816292
Almquist KC et al. Characterization of the M(r) 190,000 multidrug resistance protein (MRP) in drug-selected and transfected human tumor cell. Cancer Res 55:102-10 (1995). PubMed PMID: 7805019
Hipfner DR et al. Detection of the M(r) 190,000 multidrug resistance protein, MRP, with monoclonal antibodies. Cancer Res 54:5788-92 (1994). PubMed PMID: 7954400
Cole SP et al. Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line. Science 258:1650-4 (1992). PubMed PMID: 1360704
IgG purified
Buffer System:
Preservative: 0.1% Sodium AzideConstituents: 1% BSA, 0.1M PBS
IgG purified
Cross-reacts with Human.Does not cross-react with Mouse.Not yet tested in other species.

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