discontinued

AM11174PU-M MSH6 antibody

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Mouse anti Human MSH6 SPM525

Product Description for MSH6

Mouse anti Human MSH6 SPM525.
Presentation: Purified
Product is tested for Paraffin Sections.

Properties for MSH6

Product Category Primary Antibodies
Target Category
Quantity 0.5 ml
Synonyms DNA mismatch repair protein Msh6, G/T mismatch-binding protein, GTBP, MutS-alpha 160 kDa subunit, p160
Presentation Purified
Reactivity Hu
Applications P
Clonality Monoclonal
Clone SPM525
Host Mouse
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P52701
Immunogen:
A synthetic peptide corresponding to internal region of Human MSH6 protein
GeneID:
2956
Application Immunohistochemistry on Paraffin Sections: 1/100 for 30 min at RT.
Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0 for 10-20 min followed by cooling at RT for 20 min.
Positive Control: Colon Carcinoma.
Background Defects in MSH6 are a cause of hereditary non-polyposis colorectal cancer (HNPCC) (Lynch syndrome). HNPCC is an autosomal, dominantly inherited disease associated with marked increase in cancer susceptibility. It is characterized by a familial predisposition to early onset colorectal carcinoma (crc) and extra-colonic cancers of the gastrointestinal, urological and female reproductive tracts. HNPCC is reported to be the most common form of inherited colorectal cancer in the western world. MSH6 is central to mismatch DNA repair.
Storage

Store undiluted at 2-8°C.
DO NOT FREEZE!
Shelf life: one year from despatch.

Format
Purification:
Immunoaffinity Chromatography
Buffer System:
PBS, pH 7.6
Preservatives:
0.09% Sodium Azide
Stabilizers:
1% BSA
State:
Liquid purified Ig fraction
Purified
Species Reactivity
Species reactivity (expected):
Bovine, Dog, Hamster, Mouse, Rabbit.
Specificity
Specificity:
This antibody recognizes Human MSH6.
Gene ID 2956

Accessory Products

Proteins and/or Positive Controls

Proteins for MSH6 (2 products)

Catalog No. Species Pres. Purity   Source  

MSH6

MSH6 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

MSH6

MSH6 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Positive controls for MSH6 (1 products)

Catalog No. Species Pres. Purity   Source  

MSH6 Lysate

Western Blot: MSH6 Lysate [NBL1-13328] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for MSH6
  Novus Biologicals Inc.
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