AM05916PU-N Mycobacterium tuberculosis antibody

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Mouse anti Mycobacterium tuberculosis 5176


Product Description for Mycobacterium tuberculosis

Mouse anti Mycobacterium tuberculosis 5176.
Presentation: Purified
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot.

Properties for Mycobacterium tuberculosis

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms M. tuberculosis, TB
Presentation Purified
Applications E, WB
Clonality Monoclonal
Clone 5176
Host Mouse
Isotype IgG2a
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Swiss Prot Num:
Isotype control AM03096PU-N
Application ELISA.
Western blot.
Background Mycobacterium tuberculosis is the most common cause of tuberculosis. Primary infection begins with inhalation of 1 to 10 aerosolised bacilli. The pathogenicity of the organism is determined by its ability to escape host immune responses as well as eliciting delayed hypersensitivity. Alveolar macrophages engulf the invading cells but are unable to mount an effective defense. Several virulence factors are responsible for this apparent failure; most notably in the mycobacterial cell wall are the cord factor, lipoarabinomannan, and the 65 kd heat shock protein or HSP65.
The emergence of new strains of resistant Mycobacterium tuberculosis has created new interest in clinical diagnosis. Studies have shown immunohistochemical techniques to be superior to conventional special stains. Thus the demonstration of mycobacterial antigens are not only useful in establishing mycobacterial aetiology, but can also be used as an alternative method to the conventional Ziehl-Neelsen method.
Concentration 0.1 mg/ml
Storage Store the antibody undiluted at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf life: one year from despatch.
Affinity chromatography on Protein A
Buffer System:
Phosphate buffered saline, 0.09% Sodium Azide (NaN3)
Purified IgG prepared by affinity chromatography on Protein A
Liquid Ig fraction
This antibody is specific for the 16 kDa antigen of Mycobacterium tuberculosis and Mycobacterium bovis. M. tuberculosis is the common causative agent of tuberculosis in humans. M. bovis is a closely related species which causes tuberculosis in cattle.
Gene ID 887579

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