NB100-263SS Nbs1 antibody

See related secondary antibodies

Search for all "Nbs1"

Quick Overview

Rabbit anti Mouse Nbs1


Product Description for Nbs1

Rabbit anti Mouse Nbs1.
Product is tested for Western blot / Immunoblot.

Properties for Nbs1

Product Category Primary Antibodies
Quantity 0.025 ml
Reactivity Ms
Applications WB
Clonality Polyclonal
Host Rabbit
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

A synthetic peptide made to mouse NBS1, phosphorylated at Ser343.
Background The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex. This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity, thus revealing a direct molecular link between double-strand break repair and cell cycle checkpoint functions.
General Readings
  1. Williams, B.R., et al. A murine model of Nijmegen breakage syndrome. Curr. Biol. 12(8): 658-653, 2002. (Mouse)
  2. Falck J, Petrini JH, Williams BR, Lukas J, Bartek J. The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways. Nat Genet. 2002 Mar;30(3):290-4. Epub 2002 Feb 19. PubMed PMID: 11850621.
This antibody is specific for mouse NBS1 phosphorylated at Ser343. For human NBS1 phosphorylated at Ser343, use NB 100-284.

Accessory Products

  • LinkedIn