BP941 Neuraminidase antibody

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Rabbit anti Bacteria Neuraminidase


Product Description for Neuraminidase

Rabbit anti Bacteria Neuraminidase.
Presentation: Purified
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot.

Properties for Neuraminidase

Product Category Primary Antibodies
Quantity 1 ml
Presentation Purified
Reactivity Bac
Applications E, WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Native Neuraminidase, from C. perfringens
Application ELISA.
Western blot (1/50 - 1/200).
Background Neuraminidases or sialidases are exoglycosidases that catalyze the cleavage of a glycosidically linked terminal N acetyl neuraminic acid from sialylated glycoconjugates. They are widely spread in nature, occurring in viruses, bacteria, fungi, protozoa, birds and mammals. Together, the neuraminidases form a family of hydrolases that share a conserved active site and similar sequence motifs. Three types of neuraminidase are found in mammals and are defined as lysosomal, plasma membrane and cytosolic on the basis of their biochemical properties and subcellular distribution. Lysosomal N acetylneuraminidase (NEU1) has significant primary structure characteristics of other mammalian and microbial sialidases with similar substrate specificity. However, unlike other members of this family, lysosomal neuraminidase requires the carboxypeptidase protective protein/cathepsin A (PPCA) for intracellular transport and lysosomal activation. The enzyme is only catalytically active when it is bound to PPCA and is a component of a high molecular weight, multi protein complex containing PPCA, ß galactosidase and Nacetylgalactosamine 6 sulfate sulfatase. The autosomal recessive genetic deficiency of NEU1 is associated with sialidosis, a neurodegenerative lysosomal storage disorder.
Concentration 1.7 mg/ml
Storage Store the antibody at -20 °C. Can be shipped at 2 - 8 °C.
Avoid repeated freezing and thawing.
Shelf life: One year from despatch.
Ammonium Sulphate fractionation
Buffer System:
PBS, pH 7.2, 0.09 % Sodium Azide
Liquid Ig fraction
This antibody detects Neuraminidase.

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