GTX48741 Nicotinic Acetylcholine Receptor alpha 7 antibody

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0.1 mg / €350.00

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Rabbit anti Human Nicotinic Acetylcholine Receptor alpha 7


Product Description for Nicotinic Acetylcholine Receptor alpha 7

Rabbit anti Human Nicotinic Acetylcholine Receptor alpha 7.
Presentation: Purified
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot.

Properties for Nicotinic Acetylcholine Receptor alpha 7

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Purified
Reactivity Hu
Applications E, WB
Clonality Polyclonal
Host Rabbit
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Synthetic peptide derived from a region between amino acids 398-443.(Note: The exact amino acid sequence is proprietary).
Application ELISA, WB
Background The Nicotinic Acetylcholine Receptors are members of a superfamily of ligand gated ion channels that mediate fast signal transmission at synapses. These receptors are thought to be hetero pentamers composed of homologous subunits. The proposed structure for each subunit is a conserved N terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C terminal extracellular region. The Nicotinic Acetylcholine Receptor alpha 7 forms a homo oligomeric channel, displays marked permeability to calcium ions and is a major component of brain nicotinic receptors that are blocked by, and highly sensitive to, alpha bungarotoxin. Once this receptor binds acetylcholine, it undergoes an extensive change in conformation that affects all subunits and leads to opening of an ion conducting channel across the plasma membrane.
Concentration 2 mg/ml
Storage Upon receipt - Keep as concentrated solution. Aliquot and store at -20
Protein A affinity purified
Buffer System:
Preservative: None. Constituents: 2% Sucrose, PBS.
Protein A affinity purified
Reacts with Human.Not yet tested in other species.

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