discontinued

GTX28111 NIK antibody

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0.1 mg / €410.00

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Rabbit anti Human NIK

Product Description for NIK

Rabbit anti Human NIK.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for NIK

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Aff - Purified
Reactivity Hu
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Immunogen
Immunogen:
Synthetic peptide - amino acids 931-947 of Human NIK
Application WB
Background Nuclear factor kappa B (NF-kB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kB mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFa, LPS and mitogens. A serine/threonine protein kinase, which mediates NF-kB activation by IL-1, TNFa and CD95, was identified recently and designated NIK (for NF-kB inducing kinase)(1). NIK is an activator of IkB kinase alpha and beta (IKKa and IKKb) (2-5). Therefore, NIK is a key molecule in the NF-kB signaling pathway leading to the induction of a variety of gene expression in response to pro-inflammatory cytokines and bacteria products.
Concentration 0.5 mg/ml
Storage Keep as concentrated solution. Aliquot and store at -20
Format
Purification:
Affinity purified with antigen
Buffer System:
Phosphate-buffered saline, pH 7.4 containing 0.02% sodium azide
Purity:
Affinity purified with antigen
State:
Liquid
Aff - Purified
Specificity
Specificity:
Human - Not yet tested in other species

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