discontinued

NB100-64248 NKG2A/C/E antibody

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Search for all "NKG2A/C/E"

0.25 mg / €390.00

Quick Overview

Rat anti Mouse NKG2A/C/E 20d5

NB100-64248

Product Description for NKG2A/C/E

Rat anti Mouse NKG2A/C/E 20d5.
Presentation: Purified
Product is tested for Flow Cytometry.

Properties for NKG2A/C/E

Product Category Primary Antibodies
Quantity 0.25 mg
Synonyms CD159a, CD159c, CD159e, NKG2 lectin-like family
Presentation Purified
Reactivity Ms
Applications F
Clonality Monoclonal
Clone 20d5
Host Rat
Isotype IgG2a
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9WTJ9
Immunogen:
CHO transfected cells expressing the B6 allele of NKG2A.
GeneID:
16642
Application flow cytometry / FACS analysis, This antibody is useful for flow cytometry / FACS analysis, flow cytometry / FACS analysis 1/25 - 1/100
Background NKG2A, NKG2C and NKG2E, are isoforms of the NKG2 lectin-like family. In mice, NKG2 subunits associate with CD94 to form heterodimers at the surface of natural killer (NK) cells.The CD94/NKG2 heterodimer is the receptor for a non-classical MHC class I ligand, which is Qa 1 in the mouse. NKG2 is expressed on NK cells, lymphokine-activated killer (LAK) T cells, and some CD8+ memory T cells.
Concentration 1 mg/ml
General Readings
  1. Vance RE, Jamieson AM, Raulet DH. Recognition of the class Ib molecule Qa-1(b) by putative activating receptors CD94/NKG2C and CD94/NKG2E on mouse natural killer cells. J Exp Med. 1999 Dec 20;190(12):1801-12. PubMed PMID: 10601355. (Free PMC Article available, 7 images available)
  2. Vance RE, Jamieson AM, Cado D, Raulet DH. Implications of CD94 deficiency and monoallelic NKG2A expression for natural killer cell development and repertoire formation. Proc Natl Acad Sci U S A. 2002 Jan 22;99(2):868-73. Epub 2002 Jan 8. PubMed PMID: 11782535. (Free PMC Article available, 5 images available)
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Format
Purification:
protein G purified
Buffer System:
0.09% Sodium Azide
Purity:
protein G purified
State:
Purified
Specificity
Specificity:
NB100-64248 recognizes murine NKG2A, NKG2C and NKG2E, which are isoforms of the NKG2 lectin-like family.In mice, NKG2 subunits associate with CD94 to form heterodimers at the surface of natural killer (NK) cells.The CD94/NKG2 heterodimer is the receptor for a non-classical MHC class I ligand, which is Qa-1 in the mouse. Clone 20d5 is reported to block ligand binding to the receptor.
Species:
Mouse
Gene ID 16642

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