NB100-66000 Norgestrel antibody

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Rabbit anti Norgestrel


Product Description for Norgestrel

Rabbit anti Norgestrel.
Product is tested for Radioimmunoassay.

Properties for Norgestrel

Product Category Primary Antibodies
Quantity 250 Tests
Synonyms 13S, 14S, 17R, 8R, 9S
Applications R
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Synthetic peptide corresponding to part of the native molecule conjugated to Bovine Serum Albumin.
Application , This antibody is useful for Radioimmunoassays, Radioimmunoassay 1/250
Background Norgestrel is used as a female contraceptive. Norgestrel is a progestin or a synthetic form of the naturally occurring female sex hormone, progesterone. In a woman's normal menstrual cycle, an egg matures and is released from the ovaries (ovulation). The ovary then produces progesterone, preventing the release of further eggs and priming the lining of the womb for a possible pregnancy. If pregnancy occurs, progesterone levels in the body remain high, maintaining the womb lining. If pregnancy does not occur, progesterone levels in the body fall, resulting in a menstrual period. Norgestrel tricks the body processes into thinking that ovulation has already occurred, by maintaining high levels of the synthetic progesterone. This prevents the release of eggs from the ovaries. Norgestrel binds to the progesterone and estrogen receptors. Target cells include the female reproductive tract, the mammary gland, the hypothalamus, and the pituitary. Once bound to the receptor, progestins like Norgestrel will slow the frequency of release of gonadotropin releasing hormone (GnRH) from the hypothalamus and blunt the pre-ovulatory LH (luteinizing hormone) surge.
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer System:
Sodium Azide
D-Norgestrel 100% Rac-5A-Dihydro-Norgestrel 97% Rac-5A-Dihydro-Norgestrel-3B-ol 28% Rac-5B-Dihydro-Norgestrel 25% Rac-5B-Dihydro-Norgestrel-3A-ol 3.6% D-Norgestrel caproate <0.4%

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