discontinued

bs-11429R NPS/Neuropeptide S antibody

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0.1 ml / €240.00

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Rabbit anti Rat NPS/Neuropeptide S

bs-11429R

Product Description for NPS/Neuropeptide S

Rabbit anti Rat NPS/Neuropeptide S.
Presentation: Purified
Product is tested for Paraffin Sections.

Properties for NPS/Neuropeptide S

Product Category Primary Antibodies
Quantity 0.1 ml
Synonyms NPS, NPS_RAT., Neuropeptide-S, NeuropeptideS
Presentation Purified
Reactivity Rt
Applications P
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer Bioss, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
P0C0P7
Immunogen:
KLH conjugated synthetic peptide derived from rat Neuropeptide S.
GeneID:
100360071
Application IHC-P(1:100-500)
IF(IHC-P)(1:50-200)
Background Neuropeptides are regulators of synaptic transmission and their effects are mediated by G-protein coupled receptors. NPS (Neuropeptide S) is a 20 amino acid peptide cleaved from a larger precursor that contains a hydrophobic signal peptide and proteolytic cleavage processing sites. The N-terminal residue of NPS is always a serine regardless of the species. NPS is predominantly found in the central nervous system and plays an important role regulating sleep/wake functions, locomotion, arousal/anxiety responses and food intake. NPS functions by binding and activating its receptor, NPSR, and increasing intracellular calcium levels thereby acting as an excitatory transmitter. In addition, NPS stimulates the hypothalamo-pituitary adrenal (HPA) axis via the release of corticotropin-releasing factor (CRF) and arginine vasopressin (AVP). NPS and its receptor NPSR may also play a role in asthma pathogenesis.
Storage Store at -20°C for 12 months.
Format
Purification:
Purified by Protein A.
Buffer System:
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.
State:
Purified

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