AP22491PU-N NR1H2 (2-15) antibody

See related secondary antibodies

Search for all "NR1H2"

50 µg / €380.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

Goat anti Human NR1H2

AP22491PU-N

More Views

  • AP22491PU-N
  • AP22491PU-N

Product Description for NR1H2

Goat anti Human NR1H2.
Properties: (2-15)
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Paraffin Sections, Western blot / Immunoblot.

Properties for NR1H2

Product Category Primary Antibodies
Target Category
Quantity 50 µg
Synonyms LXRB, Liver X receptor beta, NER, Nuclear orphan receptor LXR-beta, Nuclear receptor NER, Nuclear receptor subfamily 1 group H member 2, Oxysterols receptor LXR-beta, UNR, Ubiquitously-expressed nuclear receptor
Presentation Aff - Purified
Reactivity Elephant, Hu
Applications E, P, WB
Clonality Polyclonal
Host Goat
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P55055
Immunogen:
Synthetic peptide from (N-term) of human NR1H2
AA Sequence:
SSPTTSSLDTPLPGC
GeneID:
7376
Remarks:
Percent identity by BLAST analysis: Human, Gorilla, Gibbon (100%); Marmoset, Rat, Panda, Dog, Pig (93%); Monkey, Mouse, Hamster, Elephant, Rabbit (86%)
Property 2-15
Application ELISA: 1/64000.
Immunohistochemistry on Paraffin Sections: 3 µg/ml.
Western Blot: 1 - 3 µg/ml.
Background Liver X receptor beta (LXR beta), a NR1 thyroid hormone-like receptor, has been shown to affect cholesterol and bile acid metabolism, as well as fatty acid metabolism. LXR beta mediates gene products controlling intracellular cholesterol homeostasis through the interaction with oxysterols including 22(R)-hydroxycholesterol, 24(S)-hydroxycholesterol, and 24(S),25-epoxycholesterol. LXR beta binds as a heterodimer to target sequences with retinoid X receptors and has been shown to activate a diverse set of genes involved in cholesterol and fatty acid metabolism, including ABCA1, ABCG5, ABCG8, SREBP-1c, fatty acid synthase (FAS), and the apoE/C-I/C-IV/C-II gene cluster upon ligand activation. Recently both LXR alpha and LXR beta have been shown to be important factors in atherosclerosis (Tangirala et al. 2002).
Concentration 0.5 mg/ml
Storage Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Immunoaffinity chromatography
Buffer System:
Tris saline buffer, pH 7.3, 0.5% BSA, 0.02% sodium azide
State:
Liquid Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human, Gorilla, Gibbon, Marmoset, Rat, Panda, Dog, Pig, Monkey, Mouse, Hamster, Elephant, Rabbit
Specificity
Specificity:
This antibody detects NR1H2 (N-term).
Gene ID 7376

Accessory Products

Proteins and/or Positive Controls

Proteins for NR1H2 (3 products)

Catalog No. Species Pres. Purity   Source  

NR1H2

NR1H2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €438.00
  OriGene Technologies, Inc.

NR1H2

NR1H2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

NR1H2

NR1H2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.
  • LinkedIn