TA347013 NUP98 / ADAR2 antibody

Mouse Monoclonal NUP98 Antibody

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0.1 ml / €335.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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Mouse anti NUP98 / ADAR2 3B8-D7-H10

TA347013

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  • TA347013

Product Description for NUP98 / ADAR2

Mouse anti NUP98 / ADAR2 3B8-D7-H10.
Presentation: Purified
Product is tested for Western blot / Immunoblot.

Properties for NUP98 / ADAR2

Product Category Primary Antibodies
Target Category
Quantity 0.1 ml
Synonyms Nuclear pore complex protein Nup98-Nup96
Presentation Purified
Applications WB
Clonality Monoclonal
Clone 3B8-D7-H10
Host Mouse
Isotype IgG1
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
P52948
Immunogen:
The immunogen for NUP98 antibody: purified recombinant human NUP98 protein fragments expressed in E.coli.
GeneID:
4928
Isotype control AM03095PU-N
Application WB: 1:1000
Background Sigl-mediated nuclear import and export proceed through the nuclear pore complex (NPC), which is comprised of approximately 50 unique proteins collectively known as nucleoporins. The 98 kDa nucleoporin is generated through a biogenesis pathway that involves synthesis and proteolytic cleavage of a 186 kDa precursor protein. This cleavage results in the 98 kDa nucleoporin as well as a 96 kDa nucleoporin, both of which are localized to the nucleoplasmic side of the NPC. Rat studies show that the 98 kDa nucleoporin functions as one of several docking site nucleoporins of transport substrates. The human gene has been shown to fuse to several genes following chromosome translocations in acute myelogenous leukemia (AML) and T-cell acute lymphocytic leukemia (T-ALL). This gene is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Altertive splicing of this gene results in several transcript variants; however, not all variants have been fully described.
Format
Purification:
Affinity purified
Buffer System:
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.02% sodium azide, 50% glycerol.
State:
Purified

Accessory Products

Proteins and/or Positive Controls

Proteins for NUP98 / ADAR2 (4 products)

Catalog No. Species Pres. Purity   Source  

NUP98 / ADAR2

NUP98 / ADAR2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

NUP98 / ADAR2

NUP98 / ADAR2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

NUP98 / ADAR2

NUP98 / ADAR2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

NUP98 / ADAR2

NUP98 / ADAR2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Positive controls for NUP98 / ADAR2 (1 products)

Catalog No. Species Pres. Purity   Source  

NUP98 293T Cell Transient Overexpression Lysate(Denatured)

NUP98 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.
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