ARP58648_P050 OGDH antibody

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50 µg / €350.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Bovine, Canine, Chicken, Human, Mouse, Rat OGDH

Product Description for OGDH

Rabbit anti Bovine, Canine, Chicken, Human, Mouse, Rat OGDH.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for OGDH

Product Category Primary Antibodies
Quantity 50 µg
Synonyms AKGDH, E1k, OGDC
Presentation Aff - Purified
Reactivity Bov, Can, Chk, Hu, Ms, Rt
Applications WB
Clonality Polyclonal
Host Rabbit
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer AVIVA Systems Biology

Datasheet Extract

Immunogen
Swiss Prot Num:
Q96DD3
Immunogen:
Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human OGDH with an internal ID of P35785
GeneID:
4967
Add. information Rabbit Ig G is purified by peptide affinity chromatography method. 47kDa
Application Suggested dilution at 1 ELISA titre using peptide based assay: 1:12500
Background The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO2. It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitocondrial matrix and uses thiamine pyrophosphate as a cofactor. A congential deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia.
General Readings van (2007) Am. J. Med. Genet. A 143 (7), 763-767
Storage Antibody is lyophilized from PBS buffer with 2% sucrose. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage, store at -20DegC. Avoid repeat freeze-thaw cycles.
Format
Purification:
Rabbit Ig G is purified by peptide affinity chromatography method.
Buffer System:
Antibody is lyophilized from PBS buffer with 2% sucrose. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage, store at -20DegC. Avoid repeat freeze-thaw cycles.
State:
Aff - Purified
Specificity
Species:
Human
Gene ID 4967

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