AM00507PU-N Oligodendrocytes antibody

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Mouse anti Human, Rat Oligodendrocytes HPC-7


Product Description for Oligodendrocytes

Mouse anti Human, Rat Oligodendrocytes HPC-7.
Presentation: Purified
Product is tested for Immunocytochemistry/Immunofluorescence.

Properties for Oligodendrocytes

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Purified
Reactivity Hu, Rt
Applications ICC/IF
Clonality Monoclonal
Clone HPC-7
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Rat hippocampal membranes
Isotype control AM03095PU-N, SM10P (for use in human samples), SM20P (for use in rat samples)
Add. information Mol. Wt. of Antigen: 66 kDa (rat oligodendrocytes) and 100 kDa (adult myelin)
Cellular Localization: Cell membrane
Application Immunofluorescence.
Background Myelin/oligodendrocyte-specific protein (MOSP) (pI of ~6.7) is found exclusively on oligodendrocytes and myelin in the central nervous system (CNS). Myelin is produced by oligodendrocytes in the CNS and Schwann cells in the peripheral nervous system (PNS). Defining the differences between CNS and PNS myelin may provide insights into the process of myelination and the pathogenesis of certain idiopathic diseases involving myelin such as multiple sclerosis, certain leukodystrophies, and other myelinopathies. On de-myelination, immunoreactivity for MOSP, like MBP, is lost.
Concentration 0.2 mg/ml
General Readings
  1. Baas D, (1998) GLIA, 23:169-179.
  2. Fried Man B, et al. (1989) GLIA, 2:380-390.
Storage Store the antibody at 2 - 8 °C up to one month or in aliquots at -20 °C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Protein G chromatography
Buffer System:
10 mM PBS, pH 7.4, with 0.2 % BSA and 0.09 % sodium azide
Liquid purified Ig fraction
This antibody detects Oligodendrocyte.
Human, Rat.

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