discontinued

AP06257PU-N Opioid Receptor antibody

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0.1 mg / €380.00

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Rabbit anti Human, Mouse, Rat Opioid Receptor

AP06257PU-N

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  • AP06257PU-N

Product Description for Opioid Receptor

Rabbit anti Human, Mouse, Rat Opioid Receptor.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot, Paraffin Sections.

Properties for Opioid Receptor

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications P, WB
Clonality Polyclonal
Host Rabbit
Molecular weight ~ 30 to 60 kDa
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Immunogen:
Synthetic peptide, corresponding to amino acids C-terminus of Human MOR-1.
Application Western blot: 1/500-1/1000.
Immunohistochemistry on paraffin sections: 1/50-1/200.
Background Three types of opioid receptors have been cloned: mu, delta, and kappa. Opioid eceptors are seven transmembrane G-protein coupled receptors. They share a high degree of homology and are most divergent at the N- and C-termini. Activation of mu opioid receptors leads to a decrease in neuronal excitability. Most actions of exogenous opioids, such as morphine, are mediated through the µ-opioid receptor, including analgesia, tolerance and reward. In general, opioids modulate numerous central and peripheral processes including pain perception, neuroendocrine secretion and the immune response. The opioid signal is transduced from receptors through G proteins to various different effectors. Subsequent to G protein activation, several effectors are known to orchestrate the opioid signal. For example, activation of opioid receptors increases phosphatidylinositol turnover, activates K+ channels and reduces adenylyl cyclase and Ca++ channel activities.
Concentration 1.0 mg/ml
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
Buffer System:
Phosphate buffered saline (PBS), pH 7.2.
Preservatives:
0.05% sodium azide
State:
Liquid purified Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (expected):
Mouse and Rat.
Species reactivity (tested):
Human.
Specificity
Specificity:
This antibody detects endogenous levels of Opioid Receptor protein.
(region surrounding asn369)

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