AM32061PU-N Ovarian Carcinoma-associated antigen antibody

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1 ml / €260.00
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Quick Overview

Mouse anti Human Ovarian Carcinoma-associated antigen OV632

AM32061PU-N

Product Description for Ovarian Carcinoma-associated antigen

Mouse anti Human Ovarian Carcinoma-associated antigen OV632.
Presentation: Purified
Product is tested for Frozen Sections.

Properties for Ovarian Carcinoma-associated antigen

Product Category Primary Antibodies
Quantity 1 ml
Presentation Purified
Reactivity Hu
Applications C
Clonality Monoclonal
Clone OV632
Host Mouse
Isotype IgG2b
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Isotype control AM03110PU-N, SM12P
Application Immunohistochemistry on Frozen Sections: Use at 1/10 preferably in PBS. 
This antibody can only be used on frozen sections and is characterized using the indirect immunoperoxidase method. Cross reactions were investigated using the indirect immunoperoxidase method in a dilution of 1/10, which method is therefore recommended.
General Readings
  1. Immunocytochem. of malignant mesothelioma:, 1991, Journal of Pathology vol. 165, 137-143.
  2. Boerman OC, van Niekerk CC, Makkink K, Hanselaar TG, Kenemans P, Poels LG. Comparative immunohistochemical study of four monoclonal antibodies directed against ovarian carcinoma-associated antigens. Int J Gynecol Pathol. 1991;10(1):15-25. PubMed PMID: 2007534.
  3. Delahaye M, Hoogsteden HC, Van der Kwast TH. Immunocytochemistry of malignant mesothelioma: OV632 as a marker of malignant mesothelioma. J Pathol. 1991 Oct;165(2):137-43. PubMed PMID: 1744800.
  4. Boerman O, Massuger L, Makkink K, Thomas C, Kenemans P, Poels L. Comparative in vitro binding characteristics and biodistribution in tumor-bearing athymic mice of anti-ovarian carcinoma monoclonal antibodies. Anticancer Res. 1990 Sep-Oct;10(5A):1289-95. PubMed PMID: 2241105.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Protein A Chromatography
Buffer System:
PBS
Preservatives:
0.09% Sodium Azide
Stabilizers:
1% BSA
State:
Liquid purified IgG fraction
Purified
Species Reactivity
Species reactivity (tested):
Human.
Specificity
Specificity:
This antibody clone OV632 stains 80% of non-mucinous primary and metastatic ovarian cancers. This monoclonal antibody is used for the identification of primary and metastatic nonmucinous ovarian carcinoma and ovarian carcinoma cells in peritoneal fluids. It rarely stains nongynecological malignancies using standard immunohistochemical conditions.  

Cross reactivities:
breast carcinomas: not detectable
colon carcinomas: not detectable
other nongynecological malignancies: incidentally present 
other gynecological adenocarcinomas: present
mesothelial cells: not detectable
mesotheliom: present

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