BM5550 Ovarian Carcinoma-associated antigen antibody

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Mouse anti Human Ovarian Carcinoma-associated antigen OV632


Product Description for Ovarian Carcinoma-associated antigen

Mouse anti Human Ovarian Carcinoma-associated antigen OV632.
Presentation: Ascites
Product is tested for Frozen Sections, Immunocytochemistry/Immunofluorescence.

Properties for Ovarian Carcinoma-associated antigen

Product Category Primary Antibodies
Quantity 1 ml
Presentation Ascites
Reactivity Hu
Applications C, ICC/IF
Clonality Monoclonal
Clone OV632
Host Mouse
Isotype IgG2b
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Cyst fluid from a serous cystadenocarcinoma.
Application Immunohistochemistry of frozen sections: 1:5 - 1:10; 1 h at room temperature.
General Readings
  1. Fleuren GJ, Coerkamp EG, Nap M, vd Broek LJ, Warnaar SO. Immunohistological characterization of a monoclonal antibody (OV632) against epithelial ovarian carcinomas. Virchows Arch A Pathol Anat Histopathol. 1987;410(6):481-6. PubMed PMID: 3105167.
  2. Koelma IA, Nap M, van Steenis GJ, Fleuren GJ. Tumor markers for ovarian cancer. A comparative immunohistochemical and immunocytochemical study of two commercial monoclonal antibodies (OV632 and OC125). Am J Clin Pathol. 1988 Oct;90(4):391-6. PubMed PMID: 2459953.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Buffer System:
PBS with 1% BSA and 0.1% Na-Azide
Liquid Ascites
Antibody OV632 can distinguish ovarian carcinoma from a variety of other tumors. Most primary non-mucinous ovarian adenocarcinomas react with OV632, whereas colon carcinomas and breast carcinomas do not. In surgical pathology the antibody is useful for the discrimination between ovarian and non-ovarian carcinomas both in the ovary and in cases of adenocarcinoma of unknown origin and in the abdomal cavity. Immunohistochemistry: positive staining in fallopian tube epithelium and follicular cells of ovary. Focal positive staining in epithelial cells from appendix, pancreas and prostate.

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