discontinued

NBP1-00982 P-ITGB1 antibody

See related secondary antibodies

Search for all "P-ITGB1"

0.1 mg / €390.00

Quick Overview

Rabbit anti Human, Mouse, Rat P-ITGB1

NBP1-00982

More Views

  • NBP1-00982

Product Description for P-ITGB1

Rabbit anti Human, Mouse, Rat P-ITGB1.
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Paraffin Sections, Western blot / Immunoblot.

Properties for P-ITGB1

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications E, P, WB
Clonality Polyclonal
Host Rabbit
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Application ELISA, immunohistochemistry, Western Blot, This antibody is useful for the following applications and dilutions: ELISA 1:1000-1:5000, Western Blot 1:500-1:1000, immunohistochemistry 1:50-1:200,, ELISA 1:1000-1:5000, Western Blot 1:500-1:1000, immunohistochemistry 1:50-1:200,
Background The Wiskott-Aldrich syndrome (WAS) is characterized by thrombocytopenia, eczema, defects in cell-mediated and humoral immunity and a propensity for lymphoproliferative diseases. The syndrome is the result of a mutation in the gene encoding a 53 kDa, proline-rich protein termed WASP. WASP has been identified as a downstream effector of Cdc42 and has been implicated in actin polymerization and cytoskeletal organization. A distantly related protein, VASP (vasodilator-stimulated phosphoprotein), is involved in the maintenance of cytoarchitecture by interacting with actin-like filaments. VASP shares a limited degree of homology with the amino terminus of WASP, which is frequently mutated in WAS patients. An established substrate of cAMP and cGMP dependent kinases, VASP is phosphorylated on a regulatory serine residue 157 and localizes to focal adhesions, microfilaments and highly active regions of the plasma membrane. VASP is a protein of between 46 and 50 kDa that is highly expressed in human platelets and, like WASP, may play a role in cytoskeletal organization.
Concentration 1 mg/ml
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Format
Purification:
Immunogen affinity purified
Buffer System:
15mM Sodium Azide
Purity:
Immunogen affinity purified
State:
Aff - Purified
Specificity
Specificity:
P-ITGB1
Species:
Human, Mouse, Rat

Accessory Products

  • LinkedIn