discontinued

BM555B pan Cytokeratin (4+5+6+8+10+13+18) antibody

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0.1 mg / €270.00

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Mouse anti Human, Mammalia pan Cytokeratin C-11

Product Description for pan Cytokeratin

Mouse anti Human, Mammalia pan Cytokeratin C-11.
Properties: (4+5+6+8+10+13+18)
Presentation: Biotin
Product is tested for Flow Cytometry.

Properties for pan Cytokeratin

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms Cytokeratin pan-reactive, pan Keratin
Presentation Biotin
Reactivity Hu, Mam
Applications F
Clonality Monoclonal
Clone C-11
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Immunogen:
Keratin-enriched preparation from human epidermoid carcinoma cell line A431
Property 4+5+6+8+10+13+18
Isotype control SM10B (for use in human samples)
Application Indirect immunofluorescence analysis by Flow Cytometry.
Background Cytokeratins are a subfamily of intermediate filaments and characterized by remarkable biochemical diversity. Cytokeratins are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families.
Concentration 1.0 mg/ml
General Readings
  1. Kovarík J, Rejthar A, Lauerová L, Vojtĕsek B, Bártková J. Monoclonal antibodies against individual cytokeratins in the detection of metastatic spread. Int J Cancer Suppl. 1988;3:50-5. PubMed PMID: 2463228.
  2. Vojtĕsek B, Stasková Z, Nenutil R, Lauerová L, Kovarík J, Rejthar A, et al. Monoclonal antibodies recognizing different epitopes of cytokeratin No.18. Folia Biol (Praha). 1989;35(6):373-82. PubMed PMID: 2483834.
  3. Bártek J, Vojtĕsek B, Stasková Z, Bártková J, Kerekés Z, Rejthar A, et al. A series of 14 new monoclonal antibodies to keratins: characterization and value in diagnostic histopathology. J Pathol. 1991 Jul;164(3):215-24. PubMed PMID: 1716305.
  4. Hamakawa H, Sumida T, Tanioka H, Sogawa K, Yamada T. Extraction of cytokeratin from the human submandibular gland and its electrophoretic analysis. Res Commun Mol Pathol Pharmacol. 1998 Aug;101(2):115-26. PubMed PMID: 9821208.
  5. Broekema M, Harmsen MC, Koerts JA, Petersen AH, van Luyn MJ, Navis G, et al. Determinants of tubular bone marrow-derived cell engraftment after renal ischemia/reperfusion in rats. Kidney Int. 2005 Dec;68(6):2572-81. PubMed PMID: 16316332.
Storage Store undiluted at 2-8°C.
DO NOT FREEZE!
Shelf life: one year from despatch.
Format
Label:
Conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.
Biotin
Buffer System:
Phosphate buffered saline (PBS)
Preservatives:
15 mM sodium azide, approx. pH 7.4
State:
Liquid purified Ig fraction
Species Reactivity
Species reactivity (tested):
Human, Mammalian
Specificity
Specificity:
This antibody reacts with Cytokeratin peptides 4, 5, 6, 8, 10, 13, 18. Cytokeratins are a member of intermediate filaments subfamily represented in epithelial tissues.

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