BM555PX pan Cytokeratin (4+5+6+8+10+13+18) antibody

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Mouse anti All Species pan Cytokeratin C-11


Product Description for pan Cytokeratin

Mouse anti All Species pan Cytokeratin C-11.
Properties: (4+5+6+8+10+13+18)
Presentation: Aff - Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Western blot / Immunoblot, Flow Cytometry, Paraffin Sections.

Properties for pan Cytokeratin

Product Category Primary Antibodies
Quantity 1 mg
Presentation Aff - Purified
Reactivity All Species
Applications F, ICC/IF, IP, P, WB
Clonality Monoclonal
Clone C-11
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Keratin-enriched preparation from human epidermoid carcinoma cell line A431.
Property 4+5+6+8+10+13+18
Application Western Blotting.
Flow Cytometry.
Immunohistochemistry (paraffin sections)
Background Cytokeratins are a subfamily of intermediate filaments and characterized by remarkable biochemical diversity. Cytokeratins are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families.
Concentration 1.0 mg/ml
General Readings
  1. Kovarík J, Rejthar A, Lauerová L, Vojtĕsek B, Bártková J. Monoclonal antibodies against individual cytokeratins in the detection of metastatic spread. Int J Cancer Suppl. 1988;3:50-5. PubMed PMID: 2463228.
  2. Bártek J, Vojtĕsek B, Stasková Z, Bártková J, Kerekés Z, Rejthar A, et al. A series of 14 new monoclonal antibodies to keratins: characterization and value in diagnostic histopathology. J Pathol. 1991 Jul;164(3):215-24. PubMed PMID: 1716305.
  3. Hamakawa H, Sumida T, Tanioka H, Sogawa K, Yamada T. Extraction of cytokeratin from the human submandibular gland and its electrophoretic analysis. Res Commun Mol Pathol Pharmacol. 1998 Aug;101(2):115-26. PubMed PMID: 9821208.
  4. Broekema M, Harmsen MC, Koerts JA, Petersen AH, van Luyn MJ, Navis G, et al. Determinants of tubular bone marrow-derived cell engraftment after renal ischemia/reperfusion in rats. Kidney Int. 2005 Dec;68(6):2572-81. PubMed PMID: 16316332.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Protein-A affinity chromatography.
Buffer System:
PBS, pH 7.4 containing 15 mM sodium azide as preservative.
Liquid purified IgG fraction (> 95% pure by SDS-PAGE).
Aff - Purified
The antibody C-11 reacts with Cytokeratin peptides 4, 5, 6, 8, 10, 13, 18. Cytokeratins are a member of intermediate filaments subfamily represented in epithelial tissues.

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