BM555S pan Cytokeratin (4+5+6+8+10+13+18) antibody

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0.1 mg / €210.00
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Mouse anti Amphibian, Mammalia pan Cytokeratin C-11

BM555S

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Product Description for pan Cytokeratin

Mouse anti Amphibian, Mammalia pan Cytokeratin C-11.
Properties: (4+5+6+8+10+13+18)
Presentation: Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Western blot / Immunoblot, Flow Cytometry, Paraffin Sections.

Properties for pan Cytokeratin

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms Cytokeratin pan-reactive, pan Keratin
Presentation Purified
Reactivity Amph, Mam
Applications F, ICC/IF, IP, P, WB
Clonality Monoclonal
Clone C-11
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Immunogen:
Keratin-enriched preparation from human epidermoid carcinoma cell line A431
Property 4+5+6+8+10+13+18
Isotype control AM03095PU-N
Application Western Blot.
Flow Cytometry: 0.5 µg/ml.
Immunoprecipitation.
Immunocytochemistry.
Immunohistochemistry on Paraffin Sections.
Background Cytokeratins are a subfamily of intermediate filaments and characterized by remarkable biochemical diversity. Cytokeratins are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families.
Concentration 1.0 mg/ml
General Readings
  1. Kovarík J, Rejthar A, Lauerová L, Vojtĕsek B, Bártková J. Monoclonal antibodies against individual cytokeratins in the detection of metastatic spread. Int J Cancer Suppl. 1988;3:50-5. PubMed PMID: 2463228.
  2. Bártek J, Vojtĕsek B, Stasková Z, Bártková J, Kerekés Z, Rejthar A, et al. A series of 14 new monoclonal antibodies to keratins: characterization and value in diagnostic histopathology. J Pathol. 1991 Jul;164(3):215-24. PubMed PMID: 1716305.
  3. Hamakawa H, Sumida T, Tanioka H, Sogawa K, Yamada T. Extraction of cytokeratin from the human submandibular gland and its electrophoretic analysis. Res Commun Mol Pathol Pharmacol. 1998 Aug;101(2):115-26. PubMed PMID: 9821208.
  4. Broekema M, Harmsen MC, Koerts JA, Petersen AH, van Luyn MJ, Navis G, et al. Determinants of tubular bone marrow-derived cell engraftment after renal ischemia/reperfusion in rats. Kidney Int. 2005 Dec;68(6):2572-81. PubMed PMID: 16316332.
  5. Vojtĕsek B, Stasková Z, Nenutil R, Lauerová L, Kovarík J, Rejthar A, et al. Monoclonal antibodies recognizing different epitopes of cytokeratin No.18. Folia Biol (Praha). 1989;35(6):373-82. PubMed PMID: 2483834.
Storage Store undiluted at 2-8°C.
DO NOT FREEZE!
Shelf life: one year from despatch.
Format
Purification:
Affinity Chromatography on Protein A
Buffer System:
PBS, pH~7.4
Preservatives:
15 mM Sodium Azide
State:
Liquid purified Ig fraction (> 95% pure by SDS-PAGE)
Purified
Species Reactivity
Species reactivity (tested):
Mammalian
Specificity
Specificity:
The antibody reacts with Cytokeratin peptides 4, 5, 6, 8, 10, 13, 18 (recognized epitope conserved within all species). Cytokeratins are a member of intermediate filaments subfamily represented in epithelial tissues.
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