AM20093PU-N Pan MAGUK (77-299) antibody

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0.1 mg / €380.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

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Mouse anti Human, Mouse, Rat, Xenopus, Zebrafish Pan MAGUK S28-86

AM20093PU-N

Product Description for Pan MAGUK

Mouse anti Human, Mouse, Rat, Xenopus, Zebrafish Pan MAGUK S28-86.
Properties: (77-299)
Presentation: Purified
Product is tested for Frozen Sections, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Western blot / Immunoblot.

Properties for Pan MAGUK

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Purified
Reactivity Hu, Ms, Rt, Xen, Ze
Applications C, ICC/IF, IP, WB
Clonality Monoclonal
Clone S28-86
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Immunogen:
Fusion protein amino acids 77-299 of Human PSD-95/Sap90.
Property 77-299
Isotype control AM03095PU-N, SM10P (for use in human samples), SM20P (for use in rat samples)
Application Western blot: 1 µg/ml
1 µg/ml was sufficient for detection of MAGUK proteins in 20 µg of Rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
Immunoprecipitation: 1.0-10 µg/ml
Immunofluorescence: 1.0-10 µg/ml
Immunocytochemistry: 0.1-1.0 µg/ml
Immunohistochemistry: 0.1-1.0 µg/ml
Background PDZ-domain containing proteins of the MAGUK (Membrane-Associated Guanylate Kinase) form a family of scaffolding proteins, which are often associated with cellular junctions. Their capacity to serve as platforms for organizing larger protein assemblies results from the presence of several protein-protein interaction domains (1).
PDZ-domain containing proteins of the MAGUK family target, anchor and cluster receptors and channels to subcellular sites (2).
Associations of glutamate receptors with MAGUKs have been described in the brain but not in the cochlea.
Concentration 1.0 mg/ml
General Readings
  1. Bachmann A., Draga M., Grawe F., and Knust E. (2008) BMC Dev Biol. 8:55.
  2. Davies C., Tingley D., Kachar B., Wenthold R.J., and Petralia R.S. (2001) Synapse. 40(4): 258-268.
Storage Upon receipt, store undiluted (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Protein G Chromatography.
Buffer System:
PBS, pH 7.4 containing 50% Glycerol as stabilizer and 0.09% Sodium Azide as preservative.
State:
Liquid purified Ig fraction.
Purified
Specificity
Specificity:
Detects ~95-110Da protein (varies with cell background due to phosphorylation).
Exhibits cross-reactivity against recombinant PSD-95, Chapsyn-110, SAP97 and SAP102.
Species:
Human, Mouse, Rat, Zebrafish and Xenopus.

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