TA303033 Parvalbumin alpha / PVALB (C-term) antibody

Goat Polyclonal Antibody against PVALB (C-terminal)

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Search for all "Parvalbumin alpha / PVALB"

0.1 mg / €325.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

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Goat anti Human, Rat Parvalbumin alpha / PVALB

Product Description for Parvalbumin alpha / PVALB

Goat anti Human, Rat Parvalbumin alpha / PVALB.
Properties: (C-term)
Presentation: Aff - Purified
Product is tested for Paraffin Sections, Western blot / Immunoblot.

Properties for Parvalbumin alpha / PVALB

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Presentation Aff - Purified
Reactivity Hu, Rt
Applications P, WB
Clonality Polyclonal
Host Goat
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
P20472
Immunogen:
Peptide with sequence from the C Terminus of the protein sequence according to NP_002845.1.
AA Sequence:
C-GVDEFSTLVAES
GeneID:
5816
Property C-term
Application Peptide ELISA: 1/32000 (Detection limit).
Western Blot: 0.1-0.3 µg/ml.
Approx 12kDa band observed in Human Brain lysates (calculated MW of 12.1kDa according to NP_002845.1). 
Approx 10-12kDa band observed in rat skeletal muscle and in rat heart cells transfected with human PVALB, but not in untransfected rat heart cells (Ref.1).
Immunohistochemistry on Paraffin Sections.
Background Parvalbumin (PV) is a calcium binding protein expressed in specific muscle fibers and fast-firing neurons. PV consists of a single, unbranched chain of linked amino acids and belongs to a larger group of EF hand proteins. Studies have demonstrated that parvalbumin acts in the decay of calcium in the contraction/ relaxation cycle of fast twitch muscles. This data has shown a positive correlation between the rate of relaxation and the concentration of parvalbumin.
Parvalbumin is also expressed in a specific population of GABAergic interneurones which are thought to play a role in maintaining the balance between excitation and inhibition in the cortex as well as the hippocampus. In amyotrophic lateral sclerosis (ALS) patents, parvalbumin immunoreactivity is specifically absent from neuron populations lost early in ALS.
Concentration 0.5 mg/ml
General Readings
  1. Hashimoto T, Bergen SE, Nguyen QL, Xu B, Monteggia LM, Pierri JN, et al. Relationship of brain-derived neurotrophic factor and its receptor TrkB to altered inhibitory prefrontal circuitry in schizophrenia. J Neurosci. 2005 Jan 12;25(2):372-83. PubMed PMID: 15647480.
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
Buffer System:
Tris saline, pH~7.3
Preservatives:
0.02% Sodium Azide
Stabilizers:
0.5% BSA
State:
Liquid purified IgG fraction.
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human, Rat.
Specificity
Specificity:
This antibody recognizes Parvalbumin.

Accessory Products

Proteins and/or Positive Controls

Proteins for Parvalbumin alpha / PVALB (7 products)

Catalog No. Species Pres. Purity   Source  

Parvalbumin alpha / PVALB

Parvalbumin alpha / PVALB Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Parvalbumin alpha / PVALB

Parvalbumin alpha / PVALB Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
10 µg / €299.00
  OriGene Technologies, Inc.

Parvalbumin alpha / PVALB (1-110, His-tag)

Parvalbumin alpha / PVALB Human Purified > 95 % E. coli
0.5 mg / €750.00
  Acris Antibodies GmbH

Parvalbumin alpha / PVALB (1-110, His-tag)

Parvalbumin alpha / PVALB Human Purified > 95 % E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Parvalbumin alpha / PVALB

Parvalbumin alpha / PVALB Human
  Abnova Taiwan Corp.

Parvalbumin alpha / PVALB

Parvalbumin alpha / PVALB Human Purified
  Novus Biologicals Inc.

Parvalbumin alpha / PVALB

Parvalbumin alpha / PVALB Human Purified
  Novus Biologicals Inc.
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