NB100-56830 PDAP1 antibody

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Rabbit anti Human PDAP1


Product Description for PDAP1

Rabbit anti Human PDAP1.
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay.

Properties for PDAP1

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Aff - Purified
Reactivity Hu
Applications E
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Background Principal Names: PDGF-associated protein; PAP; PAP1; PDGFA associated protein 1; Phosphatidic acid phosphotase 1; Official Gene Symbol: PDAP1 Gene ID: 11333 (Human) Gene Map Locus: 7q22.1 (Human) Platelet-derived growth factors have been directly implicated in developmental & physiological processes, as well as in human cancer, fibrotic diseases & atherosclerosis. There are 3 isoforms of PDGF: PDGF-A, B, & C. PDAP1, a 28KDa heat-and-acid stable phosphoprotein, is a novel mitogen-associated protein which binds to PDGF with low affinity. It enhances PDGF-A stimulated cell growth in mice, but lowers the mitogenic activity of PDGF-B. It catalyzes the conversion of Phosphatidic acid to diacylglycerol and is localized in the cytoplasm. Northern Blot analysis detected a ubiquitous expression of PDAP1 transcript with an exception of liver and abundant in brain.
Affinity Purified
Affinity Purified
Aff - Purified
Human Not yet tested in other species.

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