TA500625 PDE10A antibody

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0.1 ml / €325.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

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Mouse anti Human PDE10A OTI1C9

TA500625

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Product Description for PDE10A

Mouse anti Human PDE10A OTI1C9.
Presentation: Purified
Product is tested for Paraffin Sections, Western blot / Immunoblot.

Properties for PDE10A

Product Category Primary Antibodies
Target Category
Quantity 0.1 ml
Synonyms 5'-cyclic phosphodiesterase 10A, HSPDE10A, Phosphodiesterase 10A, cAMP and cAMP-inhibited cGMP 3'
Presentation Purified
Reactivity Hu
Applications P, WB
Clonality Monoclonal
Clone OTI1C9
Host Mouse
Isotype IgG2b
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9Y233
Immunogen:
Full-length protein expressed in 293T cell transfected with human PDE10A expression vector.
GeneID:
10846
Isotype control AM03110PU-N, SM12P
Application WB 1:500
IHC 1:50
Background Phosphodiesterases (PDEs) are a family of related phosphohydrolyases that selectively catalyze the hydrolysis of 3'cyclic phosphate bonds in adenosine and/or guanine 3',5' cyclic monophosphate (cAMP and/or cGMP). They regulate the cellular levels, localization and duration of action of these second messengers by controlling the rate of their degradation. There are 11 subtypes of PDEs, med PDE1-11; PDE4, 7 and 8 selectively degrade cAMP, PDE5, 6 and 9 selectively degrade cGMP and PDE1, 2, 3, 10 and 11 degrade both cyclic nucleotides. PDEs are expressed ubiquitously,with each subtype having a specific tissue distribution. These enzymes are involved in many sigl transduction pathways and their functions include vascular smooth muscle proliferation and contraction, cardiac contractility,platelet aggregation, hormone secretion, immune cell activation, and they are involved in learning and memory.
Format
Purification:
Purified from mouse ascites fluids by affinity chromatography
Buffer System:
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
State:
Purified

Accessory Products

Proteins and/or Positive Controls

Proteins for PDE10A (3 products)

Catalog No. Species Pres. Purity   Source  

PDE10A (transcript variant 2)

PDE10A Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

PDE10A

PDE10A Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

PDE10A

PDE10A Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Positive controls for PDE10A (2 products)

Catalog No. Species Pres. Purity   Source  

PDE10A Lysate

Western Blot: PDE10A Lysate [NBL1-14213] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for PDE10A
0.1 mg / €340.00
  Novus Biologicals Inc.

PDE10A overexpression lysate

PDE10A overexpression lysate
0.1 mg / €280.00
  OriGene Technologies, Inc.
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