GTX25484 PDI [RL77]-ER Marker antibody

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0.1 ml / €380.00

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Mouse anti Hamster, Human, Mouse, Porcine, Rat, Xenopus PDI [RL77]-ER Marker RL77


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  • GTX25484

Product Description for PDI [RL77]-ER Marker

Mouse anti Hamster, Human, Mouse, Porcine, Rat, Xenopus PDI [RL77]-ER Marker RL77.
Presentation: Ascites
Product is tested for Flow Cytometry, Frozen Sections, Immunoprecipitation, Western blot / Immunoblot.

Properties for PDI [RL77]-ER Marker

Product Category Primary Antibodies
Quantity 0.1 ml
Presentation Ascites
Reactivity Hst, Hu, Ms, Por, Rt, Xen
Applications C, F, IP, WB
Clonality Monoclonal
Clone RL77
Host Mouse
Isotype IgG2b
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Recombinant full length protein (Rat).
Application IHC-P, IP, WB
Background The three dimensional structure of many extracellular proteins is stabilized by the formation of disulphide bonds. Studies suggest that a microsomal enzyme known as Protein Disulphide Isomerase (PDI) is involved in disulphide-bond formation and isomerization, as well as the reduction of disulphide bonds in proteins. PDI, which catalyses disulphide interchange between thiols and protein dilsulphides, has also been referred to as thiol:protein-disulphide oxidoreductase and as glutathione:insulin transhydrogenase because of its role in reduction of disulphide bonds. The highly conserved sequence Lys-Asp-Glu-Leu (KDEL) is present at the carboxy-terminus of PDI and other soluble endoplasmic reticulum (ER) resident proteins including the 78 and 94 kDa glucose regulated proteins (GRP78 and GRP94 respectively). The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER. This retention is reported to be mediated by a KDEL receptor.
Concentration ascites fluid
Storage For long term storage, please keep at -70
Buffer System:
Preservative: 0.05% Sodium Azide; Constituents: Raw Ascites
Cross-reacts with Hamster, Human, Mouse and Rat. Not yet tested in other species.

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