BM679 Peptidoglycan antibody

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0.1 ml / €360.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Mouse anti Peptidoglycan 10H6

BM679

Product Description for Peptidoglycan

Mouse anti Peptidoglycan 10H6.
Presentation: Ascites
Product is tested for Frozen Sections, Enzyme Immunoassay.

Properties for Peptidoglycan

Product Category Primary Antibodies
Quantity 0.1 ml
Synonyms Murein
Presentation Ascites
Applications C, E
Clonality Monoclonal
Clone 10H6
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Immunogen:
This antibody was raised against insoluble PG obtained by TCA-heat and ethanol extraction of Streptococcus mutans BHT cells.
Application ELISA.
Western blot.Immunohistochemistry on Frozen Sections.
Immunohistochemistry on Paraffin Sections: Treatment with strong acid for Gram positive bacteria, or with a detergent such as SDS for Gram-negative bacteria may be necessary to expose the epitope.
General Readings
  • Miklossy, J. et al (2004) Borrelia burgdorferi persists in the brain in chronic lyme neuroborreliosis and may be associated with Alzheimer disease. J. Alzheimer's Dis. 6: 639-649.
  • Wu, L. et al. (2007) Bacterial peptidoglycan breaks down intestinal tolerance via mast cell activation: the role of TLR2 and NOD2. Immunol Cell Biol. 85: 538-45.
  • Rennemeier, C. et al. (2007) Thrombospondin-1 promotes cellular adherence of gram-positive pathogens via recognition of peptidoglycan. FASEB J. 21 (12): 3118-32.
  • Schweitzer, M.H. et al. (2016) Testing the Hypothesis of Biofilm as a Source for Soft Tissue and Cell-Like Structures Preserved in Dinosaur Bone. PLoS One. 11 (2): e0150238.
  • Miklossy J et al. (2008) Persisting atypical and cystic forms of Borrelia burgdorferi and local inflammation in Lyme neuroborreliosis. J Neuroinflammation. 5: 40.
  • Robertson, J. et al. (2016) Intestinal APCs of the endogenous nanomineral pathway fail to express PD-L1 in Crohn's disease. Sci Rep. 6: 26747.
  • Miklossy, J. (2016) Bacterial Amyloid and DNA are Important Constituents of Senile Plaques: Further Evidence of the Spirochetal and Biofilm Nature of Senile Plaques. J Alzheimers Dis. 53 (4): 1459-73.
  • Miklossy, J. et al. (2008) Type 2 Diabetes: Local Inflammation and Direct Effect of Bacterial Toxic Components The Open Pathology Journal. 2 (1): 86-95.
  • Van Gerven, N. et al. (2014) Secretion and functional display of fusion proteins through the curli biogenesis pathway. Mol Microbiol. 91 (5): 1022-35.
Storage Upon receipt, store undiluted (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
State:
Liquid Ascites without preservative or stabilizer
Ascites
Specificity
Specificity:
Reacts with the 3D polymer complex structure of peptidoglycan (PG). In a competitive immunoassay format, several compounds were found to be ineffective as inhibitors; muramyldipeptide, N-acetylglucosamine, chitin and acid hydrolyzed chitin.
The epitope appears to consist of discontinuous glycan and/or amino acid residues and has not been fully defined.

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