NB100-77863 Perforin antibody

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Mouse anti Human, Mouse Perforin dG9

Product Description for Perforin

Mouse anti Human, Mouse Perforin dG9.
Presentation: FITC
Product is tested for Immunocytochemistry/Immunofluorescence, Flow Cytometry.

Properties for Perforin

Product Category Primary Antibodies
Quantity 25 Tests
Presentation FITC
Reactivity Hu, Ms
Applications F, ICC/IF
Clonality Monoclonal
Clone dG9
Host Mouse
Isotype IgG2b
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Purified granules from the human lymphoma cell line YT
Isotype control SM12F
Application Immunocytochemistry, flow cytometry / FACS analysis
Background Perforin is a 70 kD cytolytic protein that is expressed in the cytoplasmic granules of cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells. Perforin is one of the major effector molecules used by cytotoxic T cells and NK cells to mediate targeted cell lysis. The dG9 antibody recognizes human and bovine perforin and has been shown to be useful for flow cytometry, immunoprecipitation, immunohistochemistry, and immunofluorescence staining.
General Readings
  1. Lieberman, J. 2003. Nat. Rev. Immunol. 3:361. 2. Trapani, J., et al., 2002. Nat. Rev. Immunol. 2:735.
Storage Store at 4C. Do not freeze.
Immunogen affinity purified
Buffer System:
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
Immunogen affinity purified
Human, Expected Cross-Reactivity based on immunogen sequence: Bovine (Cow, Cattle); does not cross-react with mouse1..

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