NBP1-19177 PGE2 antibody

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1 ml / €340.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti All Species PGE2


Product Description for PGE2

Rabbit anti All Species PGE2.
Product is tested for Enzyme Immunoassay, Radioimmunoassay.

Properties for PGE2

Product Category Primary Antibodies
Quantity 1 ml
Synonyms Prostaglandin E2
Reactivity All Species
Applications E, R
Clonality Polyclonal
Host Rabbit
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Prostaglandin E2
Application ELISA, This antibody is useful for ELISA., ELISA,
Background Prostaglandin E2 (PGE2) is an extensively studied prostaglandin owing to its predominance in inflammation, cancer, atherosclerosis, autoimmune disease, and sepsis. Oxidation of arachidonic acid by prostaglandin synthases (COX-1 and COX-2) produces prostaglandin H2 (PGH2), which is further metabolized by PGE synthases into its major product, PGE2. PGE2 mediates autocrine and paracrine signaling by binding to G-protein coupled receptors (EP1, EP2, EP3, EP4) on the cell surface, functioning to modulate phospholipase C and adenylate cyclase activity. PGE2 has been of great interest as a therapeutic target, either by modulation of its synthesis by COX inhibitors (NSAIDS) or by modulation of its receptors by downregulation or binding antagonists. PGE2 production in a variety of tissues has been shown to modulate numerous physiological processes including natriuresis in the kidney, smooth muscle elasticity in the vasculature, and the inflammatory response to damaged tissues by monocytes and macrophages.
Storage Store at -20C. Avoid freeze-thaw cycles.
Buffer System:
Sodium Azide
All Species

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