bs-3010R phospho-Bax (Ser184) pSer184 antibody

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Rabbit anti Human, Mouse, Rat phospho-Bax (Ser184)

Product Description for phospho-Bax (Ser184)

Rabbit anti Human, Mouse, Rat phospho-Bax (Ser184).
Properties: pSer184
Presentation: Purified
Product is tested for Western blot / Immunoblot.

Properties for phospho-Bax (Ser184)

Product Category Primary Antibodies
Quantity 0.1 ml
Presentation Purified
Reactivity Hu, Ms, Rt
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer Bioss, Inc.

Datasheet Extract

Swiss Prot Num:
KLH conjugated synthetic phosphopeptide derived from human Bax around the phosphorylation site of Ser184.
Property pSer184
Background The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Jul 2008].
Product Citations
Originator or purchased from resellers:
  1. Gao, Xiu-Fang, et al. "Urocortin-2 suppression of p38-MAPK signaling as an additional mechanism for ischemic cardioprotection." Molecular and Cellular Biochemistry: 1-12.
  2. Park, Ga Bin, et al. "Melphalan-Induced Apoptosis of EBV-Transformed B Cells through Upregulation of TAp73 and XAF1 and Nuclear Import of XPA." The Journal of Immunology (2013): 1203442.
Storage Store at -20°C for 12 months.
Purified by Protein A and peptide affinity chromatography.
Buffer System:
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.

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