discontinued

GTX80908 Phospho-p38 pThr180/pTyr182 antibody

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0.1 ml / €520.00

Quick Overview

Rabbit anti Human, Mouse, Rat Phospho-p38

GTX80908

Product Description for Phospho-p38

Rabbit anti Human, Mouse, Rat Phospho-p38.
Properties: pThr180/pTyr182
Product is tested for Western blot / Immunoblot.

Properties for Phospho-p38

Product Category Primary Antibodies
Quantity 0.1 ml
Reactivity Hu, Ms, Rt
Applications WB
Clonality Polyclonal
Host Rabbit
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Immunogen
Immunogen:
Synthetic peptide derived from human p38 that contains phosphorylated threonine 180 and tyrosine 182.
Property pThr180/pTyr182
Application WB
Background p38 participates in a cascade controlling cellular responses to cytokines and stress. Like the SAPK/JNK pathway, p38 is activated by a variety of cellular stresses including osmotic shock, inflammatory cytokines, lipopolysaccarides (LPS), and growth factors. MKK3 and SEK activate p38 by phosphorylation at Thr180 and Tyr182. Activated p38 has been shown to phosphorylate and activate MAPKAP kinase-2 and to phosphorylate the transcription factors ATF-2 and Max . Recently, a selective and potent inhibitor of p38, SB 203580, has been identified. As this compound does not inhibit SAPK, it will help to identify and distinguish functional activities mediated by SAPK and p38.
Storage -20
Format
State:
100 ul IgG in Dulbecco's PBS (without magneisum and calcium) containing 50% glycerol, 1 mg/ml BSA and 0.05% sodium azide.
Specificity
Specificity:
GTX80908 detects phospho-p38 from human, dog, mouse, and rat tissues and cells.

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