discontinued

AP00424PU-N Phosphodiesterase 9A (PDE9A) (Internal) antibody

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50 µg / €470.00

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Rabbit anti Human, Mouse, Rat Phosphodiesterase 9A (PDE9A)

Product Description for Phosphodiesterase 9A (PDE9A)

Rabbit anti Human, Mouse, Rat Phosphodiesterase 9A (PDE9A).
Properties: (Internal)
Presentation: Aff - Purified
Product is tested for Paraffin Sections.

Properties for Phosphodiesterase 9A (PDE9A)

Product Category Primary Antibodies
Quantity 50 µg
Synonyms CGMP-specific phosphodiesterase type 9, EC 3.1.4.35, HSPDE9A2, pde9A1, pde9a, pde9a2, pde9a3, pde9a4
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications P
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Immunogen:
Synthetic peptide corresponding to internal domain of human PDE9A - KLH conjugated
Property Internal
Application Immunohistochemistry: 20 µg/ml.
Background Phosphodiesterase 9A is a cGMP-specific phosphodiesterase. PDE9A activity is inhibited by zaprinast, but it is insensitive to rolipram, vinpocetine, SKF-94120, dipyridamole, and IBMX. More than 20 alternatively spliced variants have been reported (Rentero et al. 2003). PDE9A has been implicated in penile erectile dysfunction, as well as in functional disturbances in which intraneuronal signal transmission via second messengers are important in the pathophysiology (example, bipolar affective disorder). PDE9A is the only cGMP-specific PDE with significant expression in the forebrain, and as such is likely to function in NO-cGMP signaling.
Concentration 1.0 mg/ml
Storage Store the antibody at 2 - 8 °C up to one month or in aliquots at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Peptide immunogen affinity column.
Buffer System:
Phosphate buffered saline, PH 7.7 containing 0.01% sodium azide.
State:
Liquid
Aff - Purified
Specificity
Specificity:
This antibody detects Phosphodiesterase 9A.
Mouse Identity: 94 %
Mouse Similarity: 100 %
Rat Identity: 88 %
Rat Similarity: 100 %
Species:
Human, Mouse, Rat.

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