AP53299PU-N PIGP (N-term) antibody

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0.4 ml / €370.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Human PIGP

Product Description for PIGP

Rabbit anti Human PIGP.
Properties: (N-term)
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for PIGP

Product Category Primary Antibodies
Target Category
Quantity 0.4 ml
Synonyms DCRC, DCRC-S, DSCR5, DSCRC, Down syndrome critical region protein 5, Down syndrome critical region protein C, Phosphatidylinositol N-acetylglucosaminyltransferase subunit P
Presentation Aff - Purified
Reactivity Hu
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype Ig
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P57054
Immunogen:
Synthetic peptide - KLH conjugated - corresponding to the N-terminal region (between 2-30 aa) of human PIGP.
GeneID:
51227
Property N-term
Add. information Molecular Weight: 18059 Da
Application

Western blot: 1/1000.

Background The PIGP gene encodes an enzyme involved in the first step of glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. The encoded protein is a component of the GPI-N-acetylglucosaminyltransferase complex that catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI). This gene is located in the Down Syndrome critical region on chromosome 21 and is a candidate for the pathogenesis of Down syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.
Concentration lot specific.
General Readings Rose, J.E. et al., Mol. Med. 16 (7-8): 247-253 (2010)
Ferrando-Miguel, R. et al., Amino Acids 26(3): 255-261 (2004)
Choi, D.K. et al., Mamm. Genome 12(5): 347-351 (2001)
Kinoshita, T. et al., Curr Opin Chem Biol 4(6): 632-638 (2000)
Watanabe, R. et al., EMBO J. 19(16): 4402-4411 (2000)
Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Format
Purification:
Purified through a Protein A column followed by peptide affinity purification
Buffer System:
PBS with 0.09% (W/V) Sodium azide
State:
Liquid purified Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human
Specificity
Specificity:
This antibody recognizes PIGP at N-term.
Gene ID 51227

Accessory Products

Proteins and/or Positive Controls

Proteins for PIGP (4 products)

Catalog No. Species Pres. Purity   Source  

PIGP

PIGP Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

PIGP

PIGP Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

PIGP

PIGP Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

PIGP

PIGP Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Positive controls for PIGP (2 products)

Catalog No. Species Pres. Purity   Source  

PIGP Lysate

Western Blot: PIGP Lysate [NBL1-14405] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for PIGP
  Novus Biologicals Inc.

PIGP overexpression lysate

PIGP overexpression lysate
0.1 mg / €280.00
  OriGene Technologies, Inc.
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