discontinued

NB100-74517 PIP2 antibody

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0.1 ml / €400.00

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Mouse anti Human PIP2 2C11

Product Description for PIP2

Mouse anti Human PIP2 2C11.
Presentation: Ascites
Product is tested for Enzyme Immunoassay, Immunocytochemistry/Immunofluorescence, Paraffin Sections, Immunoprecipitation, Western blot / Immunoblot.

Properties for PIP2

Product Category Primary Antibodies
Quantity 0.1 ml
Synonyms 5-biphosphate, Phospatidylinositol Diphosphate, Phosphatidylinositol 4
Presentation Ascites
Reactivity Hu
Applications E, ICC/IF, IP, P, WB
Clonality Monoclonal
Clone 2C11
Host Mouse
Isotype IgM
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Immunogen:
liposomes (prepared in PBS with lipid A, phosphatidylcholine (PC) and cholesterol) containing synthetic di- palmitoyl PtdIns(4,5)P2.
Application ELISA, immunofluorescence, immunoprecipitation, Western Blot, This antibody is useful for Western Blot, immunoprecipitation, ELISA, immunofluorescence. By Western blot it detects a 67-kDa band representing NB100-74517., ELISA Assay dependent, immunofluorescence 1:200, immunoprecipitation Assay dependent, Western Blot 1:500
Background Phosphatidylinositol-4,5-bisphosphate or PIP2 is an important second messenger for a number of signaling processes. When certain extracellular signals are received Phosphilipase C cleaves phosphatidylinositol into DAG and PIP2. PIP2 has been shown to interact with actin structural proteins including profiling, gelsolin, and cofilin, and demonstrates regulatory function of actin polymerization. It has also been shown to regulate vesicular transport by interacting with proteins like ADP-ribosylation factor and phospholipase D. PIP2 has also been shown to significantly affect intracellular calcium concentrations, which also regulate a variety of activities.
Storage Store at -20C. Avoid freeze-thaw cycles.
Format
Purification:
Ascites
Buffer System:
0.05% Sodium Azide
Purity:
Ascites
State:
Ascites
Specificity
Specificity:
Prolactin-Induced Protein-1 (2C11)
Species:
Human

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