AP53312PU-N PITRM1 (Center) antibody

See related secondary antibodies

Search for all "PITRM1"

0.4 ml / €370.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Human PITRM1

Product Description for PITRM1

Rabbit anti Human PITRM1.
Properties: (Center)
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for PITRM1

Product Category Primary Antibodies
Target Category
Quantity 0.4 ml
Synonyms KIAA1104, MP1, Metalloprotease 1, Pitrilysin metalloproteinase 1, Presequence protease mitochondrial
Presentation Aff - Purified
Reactivity Hu
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype Ig
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q5JRX3
Immunogen:
KLH conjugated synthetic peptide between 497-526 amino acids from the Central region of human PITRM1
Property Center
Add. information Molecular Weight: 117455 Da
Application ELISA: 1/1000. 
Western Blot: 1/100-1/500.
Background ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference.
Concentration lot specific
General Readings Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010)
Pinho, C.M., et al. Neurosci. Lett. 469(2):204-208(2010)
Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010)
Yoshida, T., et al. Int. J. Mol. Med. 24(4):539-547(2009)
Chow, K.M., et al. Biochemistry 48(13):2868-2877(2009)
Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Format
Purification:
Protein A column, followed by peptide affinity purification
Buffer System:
PBS containing 0.09% (W/V) Sodium Azide as preservative
State:
Liquid purified Ig fraction
Aff - Purified
Specificity
Specificity:
This antibody recognizes Human PITRM1 (Center).

Accessory Products

Proteins and/or Positive Controls

Proteins for PITRM1 (2 products)

Catalog No. Species Pres. Purity   Source  

PITRM1

PITRM1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

PITRM1

PITRM1 Human in vitro transl.
  Abnova Taiwan Corp.

Positive controls for PITRM1 (2 products)

Catalog No. Species Pres. Purity   Source  

PITRM1 293T Cell Transient Overexpression Lysate(Denatured)

PITRM1 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.

PITRM1 overexpression lysate

PITRM1 overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.
  • LinkedIn