AM32826PU-S Plasma Cell antibody

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0.1 mg / €320.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Mouse anti Human Plasma Cell LIV3G11

Product Description for Plasma Cell

Mouse anti Human Plasma Cell LIV3G11.
Presentation: Purified
Product is tested for Paraffin Sections.

Properties for Plasma Cell

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms Plasma B cell, Plasmocytes
Presentation Purified
Reactivity Hu
Applications P
Clonality Monoclonal
Clone LIV3G11
Host Mouse
Isotype IgG2a
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Pancreatic cancer related serum Mucin.
Isotype control AM03096PU-N
Add. information Clone LIV3G11 is the same as 7B18
Application Immunohistochemistry on Paraffin Sections: Use Plasma Cell antibody at 0.5-1 µg/ml for 30 minutes at RT. 
Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes. 
Positive ControlTonsil or Lymph node.
Background Plasma cells (also called plasma B cells or plasmocytes), which are large lymphocytes derived from an antigen-specific B cell, secrete antibodies and are responsible for humoral immunity. Plasma cells differentiate from B cells upon stimulation by CD4+ lymphocytes. The B cell acts as an antigen-presenting cell (APC), consuming an offending pathogen, which is taken up by the B cell by phagocytosis and broken down within proteosomes. Plasma cells contain basophilic cytoplasm; their nucleus contains heterochromatin organized in a characteristic cartwheel arrangement.
Concentration 0.2 mg/ml
General Readings
  1. Turley H, Jones M, Erber W, Mayne K, de Waele M, Gatter K. VS38: a new monoclonal antibody for detecting plasma cell differentiation in routine sections. J Clin Pathol. 1994 May;47(5):418-22. PubMed PMID: 7517959. (Free PMC Article available)
  2. Ching CK and Rhodes JM. 1998. Gastroenterology; 95: 137-42.
  3. Ching CK, Rhodes JM. Purification and characterization of a peanut-agglutinin-binding pancreatic-cancer-related serum mucus glycoprotein. Int J Cancer. 1990 Jun 15;45(6):1022-7. PubMed PMID: 2351483.
Storage Store undiluted at 2-8°C.
Shelf life: one year from despatch.
Protein A/G Chromatography
Buffer System:
10mM PBS
0.05% Sodium Azide
0.05% BSA
Liquid purified IgG fraction from Bioreactor Concentrate
Species Reactivity
Species reactivity (tested):
LIV3G11 antibody recognizes an intracytoplasmic antigen which shows a very high degree of specificity for plasma cells. This antigen is present in normal as well as neoplastic plasma cells.
This monoclonal antibody superbly recognizes normal and neoplastic plasma cells in routine formalin-fixed, paraffin-embedded tissue sections. Plasma Cell Marker antibody is of potential value in identifying myeloma or plasmacytoma in bone marrow or other tissues. It also helps differentiate lymphoplasmacytoid lymphoma from lymphocytic and follicular lymphoma.  
Note that this MAb is not suitable for staining frozen tissues.
Cellular Localization: Cytoplasmic. 
Negative Species: Rat.

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