DM417 Plasminogen Activator Inhibitor I (PAI) antibody

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Mouse anti Human Plasminogen Activator Inhibitor I (PAI) TAJ6


Product Description for Plasminogen Activator Inhibitor I (PAI)

Mouse anti Human Plasminogen Activator Inhibitor I (PAI) TAJ6.
Presentation: Supernatant
Product is tested for Frozen Sections, Paraffin Sections.

Properties for Plasminogen Activator Inhibitor I (PAI)

Product Category Primary Antibodies
Quantity 1 ml
Presentation Supernatant
Reactivity Hu
Applications C, P
Clonality Monoclonal
Clone TAJ6
Host Mouse
Isotype IgG2b
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Prokaryotic recombinant protein corresponding to a 250 amino acid portion of the N-terminus of the human PAI-1.
Application Immunohistochemistry on paraffin embedded sections:
diluted of 1:10-1:25 in an ABC method (60 minutes at room temperature)
Recommended positive control: Breast or Ovarian carcinoma
Background Plasminogen Activation Inhibitor type 1 (PAI-1) inhibits the conversion of plasminogen to plasmin. It is the principal inhibitor of plasminogen activators t-PA and uPA. PAI-1 is structurally related to the serine protease inhibitor superfamily. PAI-1 protein is overexpressed in a number of malignancies including ovarian cancers and derived cell lines, endometrial cancers, cervical cancer, malignant brain cancers and nasopharyngeal carcinomas.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Buffer System:
10 mM citrate buffer, pH 6.0 - containing sodium azide as preservative.
Liquid tissue culture supernatant
This antibody recognizes a 48 kD protein.
Cellular localization: Cytoplasmic.

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