NB100-56795 PLS3 antibody

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Rabbit anti Human PLS3


Product Description for PLS3

Rabbit anti Human PLS3.
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay.

Properties for PLS3

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Aff - Purified
Reactivity Hu
Applications E
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

This antibody was developed against a synthetic peptide corresponding to amino acids 95-111 of human PLS3. This sequence is 94% homologous in mouse and 100% in rat.
Background . Often times, multiple samples will be included, differing in the amino acid sequence used to raise the immune sera. Phospholipid scramblases (PLS) translocate phospholipids bidirectionally between inner and outer leaflets of the plasma membrane and are implicated in apoptosis (1,2). Members of this family, PLS1 and PLS3 are both substrates of Protein kinase C (PKC) delta and are phosphorylated by PKC-delta during apoptosis. PKC-delta translocates to mitochondria during apoptosis and phosphorylates PLS3. Overexpression of PLS3 in the HEK293 cells enhanced apoptosis induced by UV-irradiation.
Affinity Purified
Buffer System:
PBS containing 0.2% gelatin and 0.05% sodium azide. Sodium azide is highly toxic.
Affinity Purified
Aff - Purified
Human Not yet tested in other species.

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