discontinued

ARP44994_P050 POMT1 antibody

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Quick Overview

Rabbit anti Bovine, Human, Mouse, Rat POMT1

Product Description for POMT1

Rabbit anti Bovine, Human, Mouse, Rat POMT1.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for POMT1

Product Category Primary Antibodies
Target Category
Quantity 50 µg
Synonyms Dolichyl-phosphate-mannose--protein mannosyltransferase 1, Protein O-mannosyl-transferase 1
Presentation Aff - Purified
Reactivity Bov, Hu, Ms, Rt
Applications WB
Clonality Polyclonal
Host Rabbit
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer AVIVA Systems Biology

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9Y6A1
Immunogen:
Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human POMT1 with an internal ID of P12306
GeneID:
10585
Add. information Rabbit Ig G is purified by peptide affinity chromatography method. 82kDa
Application Suggested dilution at 1 ELISA titre using peptide based assay: 1:62500
Background POMT1 is an O-mannosyltransferase that requires interaction with the product of the POMT2 gene for enzymatic function. The encoded protein is found in the membrane of the endoplasmic reticulum. Defects in this gene are a cause of Walker-Warburg syndrome (WWS) and limb-girdle muscular dystrophy type 2K (LGMD2K).O-mannosylation is an important protein modification in eukaryotes that is initiated by an evolutionarily conserved family of protein O-mannosyltransferases. POMT1 shares sequence similarity with protein O-mannosyltransferases of S. cerevisiae. In yeast, these enzymes are located in the endoplasmic reticulum (ER) and are required for cell integrity and cell wall rigidity. POMT1 also shows similarity to the Drosophila \'rotated abdomen\' (rt) gene, which when mutated causes defects in myogenesis and muscle structure.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-42 DB154785.1 1-42 43-2420 AK074874.1 1-2378 2421-2617 BF984005.1 438-634 2618-3080 AL358781.19 127610-128072
General Readings Messina,S., (er) Neuromuscul. Disord. (2008) In press
Storage Antibody is lyophilized from PBS buffer with 2% sucrose. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage, store at -20DegC. Avoid repeat freeze-thaw cycles.
Format
Purification:
Rabbit Ig G is purified by peptide affinity chromatography method.
Buffer System:
Antibody is lyophilized from PBS buffer with 2% sucrose. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage, store at -20DegC. Avoid repeat freeze-thaw cycles.
State:
Aff - Purified
Specificity
Species:
Human
Gene ID 10585

Accessory Products

Proteins and/or Positive Controls

Proteins for POMT1 (2 products)

Catalog No. Species Pres. Purity   Source  

POMT1

POMT1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

POMT1

POMT1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

Positive controls for POMT1 (1 products)

Catalog No. Species Pres. Purity   Source  

POMT1 overexpression lysate

POMT1 overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.
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