AM06358PU-N PR3 / C-ANCA antibody

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0.1 ml / €400.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Mouse anti Human PR3 / C-ANCA 3B4

Product Description for PR3 / C-ANCA

Mouse anti Human PR3 / C-ANCA 3B4.
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot.

Properties for PR3 / C-ANCA

Product Category Primary Antibodies
Target Category
Quantity 0.1 ml
Synonyms AGP7, Leukocyte proteinase 3, MBN, Myeloblastin, NP-4, Neutrophil proteinase 4, P29, PR-3, PRTN3, Proteinase 3, Wegener autoantigen
Presentation Aff - Purified
Reactivity Hu
Applications E, WB
Clonality Monoclonal
Clone 3B4
Host Mouse
Isotype IgG2b
Molecular weight 28 kDa
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P24158
Immunogen:
Purified recombinant fragment of human Proteinase 3 expressed in E. Coli.
GeneID:
5657
Application Western Blot: 1/500 - 1/2000.
ELISA: 1/10000.
Background Proteinase 3, also known as PRTN3. PRTN3 is a serine protease enzyme expressed mainly in neutrophil granulocytes. Its exact role in the function of the neutrophil is unknown but in human neutrophils proteinase 3 contributes to the proteolytic generation of antimicrobial peptides. It is also the epitope of anti-neutrophil cytoplasmic antibodies (ANCAs) of the cANCA (cytoplasmic subtype) class, a type of antibody frequently found in the disease Wegener's granulomatosis.
General Readings
  1. Blood. 2007 Dec 1;110(12):4086-95.
  2. Clin Exp Immunol. 2006 Jul;145(1):63-70.
Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Format
Purification:
Affinity chromatography on Protein G
Buffer System:
PBS
Preservatives:
0.03% sodium azide
Stabilizers:
50% glycerol
State:
Liquid purified Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human.
Specificity
Specificity:
This antibody reacts to Proteinase 3.
Gene ID 5657

Accessory Products

Proteins and/or Positive Controls

Proteins for PR3 / C-ANCA (7 products)

Catalog No. Species Pres. Purity   Source  

PR3 / C-ANCA

PR3 / C-ANCA Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

PR3 / C-ANCA

PR3 / C-ANCA Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €399.00
  OriGene Technologies, Inc.

PR3 / C-ANCA

PR3 / C-ANCA Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

PR3 / C-ANCA

PR3 / C-ANCA Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

PR3 / C-ANCA

PR3 / C-ANCA Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

PR3 / C-ANCA

PR3 / C-ANCA Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

PR3 / C-ANCA

PR3 / C-ANCA Human Purified > 96 % Neutrophils
  BBI Solutions

Positive controls for PR3 / C-ANCA (3 products)

Catalog No. Species Pres. Purity   Source  

PR3 Lysate

Western Blot: PR3 Lysate [NBL1-14851] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for PRTN3
  Novus Biologicals Inc.

PRTN3 293T Cell Transient Overexpression Lysate(Denatured)

PRTN3 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.

PRTN3 overexpression lysate

PRTN3 overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.
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