AM50154PU-S Progesterone receptor antibody

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0.1 mg / €320.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Mouse anti Human Progesterone receptor SPM566

Product Description for Progesterone receptor

Mouse anti Human Progesterone receptor SPM566.
Presentation: Purified
Product is tested for Frozen Sections, Paraffin Sections, Western blot / Immunoblot.

Properties for Progesterone receptor

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms NR3C3, Nuclear Receptor Subfamily 3 Group C Member 3, PGR, PR
Presentation Purified
Reactivity Hu
Applications C, P, WB
Clonality Monoclonal
Clone SPM566
Host Mouse
Isotype IgG1
Molecular weight PR-A (81kDa) and PR-B (116kDa).
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P06401
Immunogen:
Recombinant human Progesterone Receptor protein.
GeneID:
5241
Isotype control AM03095PU-N, SM10P (for use in human samples)
Application Western Blotting: 0.5-1 μg/ml for 2 hours at RT.
Immunohistochemistry on Frozen and Formalin-Fixed Sections: 0.5-1.0 μg/ml for 30 minutes at RT.
Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.
Recommended Positive Control: T47-D Cells or Breast Cancers.
Concentration 0.2 mg/ml
General Readings
  1. Press M, Spaulding B, Groshen S, Kaminsky D, Hagerty M, Sherman L, et al. Comparison of different antibodies for detection of progesterone receptor in breast cancer. Steroids. 2002 Aug;67(9):799-813. PubMed PMID: 12123792.
  2. Mote PA, Johnston JF, Manninen T, Tuohimaa P, Clarke CL. Detection of progesterone receptor forms A and B by immunohistochemical analysis. J Clin Pathol. 2001 Aug;54(8):624-30. PubMed PMID: 11477119. (Free PMC Article available, 2 images available)
Storage Store undiluted at 2-8°C.
Shelf life: one year from despatch.
Format
Purification:
Protein A/G Chromatography
Buffer System:
10mM PBS
Preservatives:
0.05% Sodium Azide
Stabilizers:
0.05% BSA
State:
Liquid purified IgG fraction from Bioreactor Concentrate
Purified
Specificity
Specificity:
This Monoclonal Antibody is specific to Progesterone Receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81kDa) and PR-B (116kDa). Expression of PgR has been suggested to reflect a intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone.
This Clone It is excellent for immunohistochemical staining of formalin/paraffin tissues.
Cellular Localization: Nuclear.
Species:
Human.
FocusOn and Reviews
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Accessory Products

Proteins and/or Positive Controls

Proteins for Progesterone receptor (7 products)

Catalog No. Species Pres. Purity   Source  

Progesterone receptor

Progesterone receptor Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Progesterone receptor

Progesterone receptor Human Purified E. coli
  Acris Antibodies GmbH

Progesterone receptor

Progesterone receptor Human Purified E. coli
  Acris Antibodies GmbH

Progesterone receptor

Progesterone receptor Human Purified E. coli
  Acris Antibodies GmbH

Progesterone receptor

Progesterone receptor Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Progesterone receptor

Progesterone receptor Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Progesterone receptor

Progesterone receptor Human
  Abnova Taiwan Corp.

Positive controls for Progesterone receptor (1 products)

Catalog No. Species Pres. Purity   Source  

PGR overexpression lysate

PGR overexpression lysate
0.1 mg / €480.00
  OriGene Technologies, Inc.
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