discontinued

GTX40239 Proteasome S5A [AH1.1] antibody

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0.1 mg / €410.00

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Mouse anti Mouse Proteasome S5A [AH1.1] AH1.1

GTX40239

Product Description for Proteasome S5A [AH1.1]

Mouse anti Mouse Proteasome S5A [AH1.1] AH1.1.
Presentation: Ig Fraction
Product is tested for Immunoprecipitation, Western blot / Immunoblot.

Properties for Proteasome S5A [AH1.1]

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Ig Fraction
Reactivity Ms
Applications IP, WB
Clonality Monoclonal
Clone AH1.1
Host Mouse
Isotype IgG1
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Immunogen
Immunogen:
Sub unit 5a.
Application IP, WB
Background The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This protein is one of the non-ATPase subunits of the 19S regulator lid and binds and presumably selects ubiquitin-conjugates for destruction. Two alternate transcripts encoding two different isoforms have been described. Pseudogenes have been identified on chromosomes 10 and 21.
Concentration 1 mg/ml
Storage Keep as concentrated solution. Store at 4
Format
Purification:
IgG fraction
Buffer System:
Preservative: None. Constituents: PBS
Purity:
IgG fraction
State:
Ig Fraction
Specificity
Specificity:
Cross-reacts with Mouse. Not yet tested in other species.

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