NB120-3534 Pseudorabies Virus antibody

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Rabbit anti Virus Pseudorabies Virus

Product Description for Pseudorabies Virus

Rabbit anti Virus Pseudorabies Virus.
Product is tested for Frozen Sections, Paraffin Sections, Western blot / Immunoblot.

Properties for Pseudorabies Virus

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms PRV, SuHV-1, Suid herpesvirus 1
Reactivity Vi
Applications C, P, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Purified pseudorabies virus Bartha.
Add. information Research Areas: Immunology
Application immunohistochemistry, Western Blot, By Western blot, this antibody detects proteins in the range of 80-115 kDa representing various PRV proteins. Immunohistochemical staining of PRV in rat hypothalamus from animals injected with PRV into the vitreous body of the eye results in intense staining of neurons in the superchiasmatic nucleus., immunohistochemistry F: 1.0 ug/ml, Western Blot 0.2 - 1.0 ug/ml
Background Herpes simplex virus (HSV), varicella-zoster virus (VZV) and pseudorabies virus (PRV) comprise a family of neurotropic viruses known as alphaherpesviruses. PRV is primarily a disease of swine which serve as a reservoir for the virus and the principal source of natural infection for a diverse range of secondary hosts, including cattle, sheep, goats, dogs, cats, and many feral species. Humans and apes are refractory to PRV infection. PRV infects the epithelium of the host where it then spreads to axons of the peripheral nervous system (PNS). The virus opportunistically avails itself of the neuronal retrograde transport pathway which can facilitate transfer to the brain. This unique aspect of PRV allows it to be used as a powerful research tool to study neural connectivity and trace neuronal circuitry in the peripheral (PNS) and central nervous system (CNS).
Concentration 1 mg/ml
General Readings General / background references:Brideau AD et al. The role of virion membrane protein endocytosis in the herpesvirus life cycle. J Clin Virol 17:69-82 (2000). PubMed PMID: 10942087
Billig I et al. Definition of neuronal circuitry controlling the activity of phrenic and abdominal motoneurons in the ferret using recombinant strains of pseudorabies virus. J Neurosci 20:7446-54 (2000). PubMed PMID: 11007904
Husak PJ et al. Pseudorabies virus membrane proteins gI and gE facilitate anterograde spread of infection in projection-specific neurons in the rat. J Virol 74:10975-83 (2000). PubMed PMID: 11069992
Smith BN et al. Pseudorabies virus expressing enhanced green fluorescent protein: A tool for in vitro electrophysiological analysis of transsynaptically labeled neurons in identified central nervous system circuits. Proc Natl Acad Sci U S A 97:9264-9 (2000). PubMed PMID: 10922076
Storage Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
protein A purified
Buffer System:
0.05% Sodium Azide
protein A purified
Pseudorabies Virus

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