SP5153P Pseudorabies Virus antibody

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0.1 mg / €470.00

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Rabbit anti Pseudorabies Virus

Product Description for Pseudorabies Virus

Rabbit anti Pseudorabies Virus.
Presentation: Purified
Product is tested for Frozen Sections, Western blot / Immunoblot.

Properties for Pseudorabies Virus

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms PRV, SuHV-1, Suid herpesvirus 1
Presentation Purified
Applications C, WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Purified pseudorabies virus-Bartha.
Application Immunohistochemistry on frozen sections: 1 µg/ml, staining of PRV in rat hypothalamus from animals injected with PRV into the vitreous body of the eye results in intense staining of neurons in the superchiasmatic nucleus.
Western Blot: 0.2-1 µg/ml, detects proteins in the range of 80-115 kDa representing various PRV proteins.
Background Herpes simplex virus (HSV), varicella-zoster virus (VZV) and pseudorabies virus (PRV) comprise a family of neurotropic viruses known as alphaherpesviruses. PRV is primarily a disease of swine which serve as a reservoir for the virus and the principal source of natural infection for a diverse range of secondary hosts, including cattle, sheep, goats, dogs, cats, and many feral species. Humans and apes are refractory to PRV infection. PRV infects the epithelium of the host where it then spreads to axons of the peripheral nervous system (PNS). The virus opportunistically avails itself of the neuronal retrograde transport pathway which can facilitate transfer to the brain. This unique aspect of PRV allows it to be used as a powerful research tool to study neural connectivity and trace neuronal circuitry in the peripheral (PNS) and central nervous system (CNS).
General Readings
  1. Journal of Neuroscience 24(23), 5370-5380, Jun 2004.
  2. J. Clin. Virol., 17:69-82, 2000.
  3. J. Neurosci., 20:7446-7454, 2000.
  4. J. Virol., 74:10975-10983, 2000.
Storage Store the antibody at -20°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Protein A affinity chromatography.
Buffer System:
PBS containing 1 mg/ml BSA as stabilizer and 0.05% sodium azide as preservative.
Liquid purified IgG fraction.
This antibody detects pseudorabies virus (PRV).

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